Bone hemangiopericytoma
Introduction
Introduction to osteovascular epithelial cell tumor Osteovascular epithelioma is a tumor that originated in the iliac cells of the bone vessel Zimmerman. It was first described by Stout in 1942. This tumor is extremely rare. At present, there are less than 40 cases reported in domestic and foreign literatures. In 1993, it was divided into two types: intermediate type hemangiopericytoma and malignant hemangiopericytoma. basic knowledge Sickness ratio: 0.05% Susceptible people: more common in teenagers Mode of infection: non-infectious Complications: spinal cord compression fracture
Cause
Causes of osteovascular epithelioma
Cause of the disease: the cause is unknown.
Pathogenesis:
1. Visual observation: The tumor is invasively growing, with or without obvious boundaries, varying in size, ranging from 1 to 25 cm in diameter, soft or hard or tough, cut fish-like, gray-red, with bleeding and necrosis.
2. It can be seen under the microscope: it is mainly composed of a proliferating cell band structure surrounded by abundant vascular cavities. The blood vessel wall is thin and lining a layer of flat endothelial cells. The lumen diameter is as fine as capillary, and the sinusoid is thick to the sinusoid. Tumor cells are rhomboid or elliptical, with cytoplasmic staining, round or oval nucleus, different sizes, fine chromatin, no nucleoli or only one small nucleolus, more nuclear division, and some regional tumor cells Intensive, bundled or swirling, argyrophilic staining of the vascular network of blood vessels separates tumor cells from endothelial cells, reticular fibers interspersed between tumor cells, and most tumor cells are similar to epithelial cells under electron microscope, some tumors The cell is a transitional form between the epithelial cells and the smooth muscle cells.
Prevention
Prevention of bone vascular epithelioma
1. Smoking banned alcohol: It is the primary measure to prevent throat cancer. The smoke is the hottest leader. The wine is the hottest and hottest. Smoking and drinking are extremely harmful to the pharynx.
Second, light diet: Where the ginger pepper mustard and all the spicy hot things will hurt the mucous membrane of the throat, should avoid eating these spicy and fried foods, eat more fruits and vegetables containing vitamin C.
Third, pay attention to oral hygiene: pay attention to personal hygiene, wash hands frequently. Use fresh salt water to rinse your mouth in the morning and evening.
Complication
Complication of bone vascular epithelioma Complications, spinal cord compression fractures
Occurred in the spine, may have spinal cord compression symptoms, and even paraplegia, and sometimes can be associated with rational fractures.
Symptom
Symptoms of Osteovascular Epithelial Tumors Common Symptoms Spinal Cord Compression of Anterior Paravertebral Soft Tissues... Paraplegia
Can be seen at any age, more common in adolescents, there is no significant difference in gender, the reported parts are pelvis, femur, clavicle, ribs, vertebrae, humerus, sternum and jaw, with the largest number of pelvis and femur, the reported lesions are single .
Symptoms and signs: The clinical manifestations are characterized by lack of characteristics, mainly manifested by swelling, pain and tenderness. In most cases, the painless mass is the first symptom, which is gradually aggravated, the activity is limited, and a few pains are obvious. At night, the skin temperature is swollen. Increased, venous engorgement, increased pain after pathological fracture, loss of function, occurred in the spine, may have spinal cord compression symptoms, and even paraplegia.
If adolescent patients have pain, swelling or swelling in the metaphysis or backbone, gradually worsening, limited activity, a few pains, nighttime, local skin temperature increase, venous engorgement, tenderness, imaging findings of bone eclipse Osteoporotic or flaky or foamy osteolytic destruction, residual osteophytes, unclear borders, clinical exclusion of osteolytic osteosarcoma, malignant lymphoma, metastatic carcinoma and malignant fibrous histiocytoma, should consider vascular tumors The diagnosis, because of the abnormality of hemangiopericytoma, can only be confirmed by pathological examination. This tumor is mainly composed of abundant vascular cavities and a large number of tumorous epithelial cells.
Examine
Examination of bone vascular epithelial cell tumor
Dry sputum or backbone worm-like, patchy, foamy or flaky osteolytic destruction, unclear margins, residual bone defects of varying sizes in the destruction zone, pathological fractures in severely damaged, tumor invasion And the cortical bone makes it thin and mildly dilated, and can also penetrate the cortical bone into the soft tissue to form a soft tissue mass. In a few cases, a small amount of osteogenesis can be seen, with a periosteal reaction or a Codmon triangle.
Diagnosis
Diagnosis and diagnosis of bone vascular epithelioma
Silver staining shows that the reticular fibrous membrane of the blood vessels separates the endothelial cells from the tumor cells. The reticular fibers are interspersed between the tumor cells, which can be differentiated from vascular endothelial cell tumors. There are branch or anastomotic vascular cavities under the microscope. This can be distinguished from malignant fibrous histiocytoma. In addition, histopathology should also be distinguished from synovial sarcoma, mesenchymal chondrosarcoma and metastatic cancer.
