Sodium pentachlorophenate poisoning
Introduction
Introduction to sodium pentachlorophenol poisoning Sodium pentachlorophenolate (sodiumpentachlorophenate) is currently used as a blood-killing snail, and it also kills grasshoppers, cockroaches, fruit tree pests, fungi, bacteria, etc. It can also be used as a wood preservative and agricultural herbicide. However, the toxicity to humans and animals is also large. The acute lethal dose of acute poisoning in rats is 78mg/kg, and the acute lethal dose of adults entering by various routes is 2g. Sodium pentachlorophenol stimulates the oxidation process of cells and suppresses the phosphorylation process, so that the energy generated by the stimulation of the oxidation process cannot be stored into the form of adenosine triphosphate and creatine phosphate by phosphorylation, but is released by heat energy. Series of symptoms. basic knowledge The proportion of illness: 0.005% Susceptible people: no specific population Mode of infection: non-infectious Complications: dehydration, coma, pulmonary edema, respiratory failure, interstitial pneumonia, cough
Cause
Causes of sodium pentachlorophenol poisoning
Cause:
Foods contaminated with sodium pentachlorophenolate (such as food and poisoned poultry, livestock, fish, etc.) and water, as well as inhaled or contaminated skin, can be poisoned, and elevated environmental temperatures can increase their toxic effects.
Prevention
Pentachlorophenol sodium poisoning prevention
Do a good job in health promotion:
1 Education children should not play in the application site, which can reduce the chance of infection in children.
2 It is forbidden to eat food contaminated with sodium pentachlorophenolate, water and poisoned birds, animals and fish. In the diet, we must pay attention to cleanliness and improve the safety of food.
3 It is forbidden to wash hands, feet and swim in the water to be applied.
4 This product must be kept in a safe place to prevent children from accidentally touching and eating. Put sodium pentachlorophenol in a place that is not accessible to children, so as to avoid eating in children.
Complication
Complications of sodium pentachlorophenol poisoning Complications dehydration coma pulmonary edema respiratory failure interstitial pneumonia cough
Severe convulsions, dehydration, acidosis, coma, pulmonary edema, even breathing, circulatory failure, coughing, shortness of breath, chest tightness, interstitial pneumonia.
Symptom
Symptoms of sodium pentachlorophenol poisoning Common symptoms Nausea diarrhea Abdominal pain convulsions Irritability Uncomfortable coma Dehydration Skin ecchymosis Circulatory failure
Patients exposed to or taking large amounts of sodium pentachlorophenol poisoning often develop symptoms within a few hours and can die within 24 hours. Early symptoms of mild or poisoning include headache, dizziness, loss of appetite, nausea, vomiting, abdominal pain, fatigue, heavy lower limbs and Numbness, muscle pain, sweating, fever, etc., severe poisoning is a few hours after the early symptoms appear, the condition suddenly aggravates, the patient's body temperature rises rapidly, up to 40 ° C, sweating, diarrhea, skin flushing, conjunctival congestion, Heart rate is accelerated, irritability, convulsions, extreme fatigue and weakness, body pain is obvious; some patients have skin ecchymosis, myocardial damage, blood pressure rises, and then decline, severe dehydration, acidosis, pulmonary edema, etc., and finally due to coma , death from respiratory and circulatory failure, liver and kidney damage after acute phase, respiratory mucosal irritation and interstitial pneumonia often occur in inhalation poisoning; skin contact with pentachlorophenol sodium may cause contact dermatitis, poisoning patients' blood And urine can detect phenolic compounds, often have high blood sugar and diabetes, this product is rapidly metabolized in the body, excreted quickly, No accumulation, if the patient can spend 24 hours, the prognosis is better.
Examine
Examination of sodium pentachlorophenol poisoning
Sputum, blood and urine can detect sodium pentachlorophenol, mild poisoning, sodium pentachlorophenol can exceed 37.5umol / L, severe poisoning can exceed 75umol / L; the total number of white blood cells and neutral hinge cells High, blood sodium, low blood potassium, elevated blood sugar, reduced carbon dioxide binding. The basal metabolic rate is increased and the transductase is increased.
Diagnosis
Diagnosis and identification of sodium pentachlorophenol poisoning
diagnosis
It can be diagnosed based on medical history, clinical symptoms and laboratory tests.
Differential diagnosis
Should be noted with heatstroke, influenza and other fever diseases and acute digestive diseases.
