Recurrent linear acantholytic skin disease
Introduction
Introduction to recurrent linear acantholytic dermatosis Relapsing linear acupuncture dermatosis (relapsinglinearacantholiticdermatosis) was reported by Vakilzadeh et al in 1985, and has not been reported in China. basic knowledge The proportion of illness: 0.006% - 0.007% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
The cause of recurrent linear acanthosis dermatosis
The cause of this disease is unknown. There is no evidence related to heredity and no reports related to infectious factors, but it may have a certain correlation with autoimmunity, and it has not been confirmed yet.
Prevention
Recurrent linear acanthosis dermatological prevention
prevention:
1. Keep your skin clean and hygienic;
2. Allergic skin diseases should be banned, frequent boiled water and other diseases have no effective preventive measures, early detection of early diagnosis is the key to the prevention and treatment of this disease.
Complication
Recurrent linear acanthosis dermatological complications Complication
The cause of the disease is unclear and may be related to genetic, immune, and environmental factors. Because the disease may be accompanied by itching and the integrity of the skin is destroyed, it may cause skin bacterial infection or fungal infection due to scratching, usually secondary to low constitution, or long-term use of immunosuppressants and fungal infections such as onychomycosis. Such as concurrent bacterial infections may have fever, skin swelling, ulceration and purulent secretion and other performance. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Recurrent linear acanthosis dermatological symptoms Common symptoms Itching skin blisters, posterior... Burning pain
Skin lesions are limited to one side of the body, arranged in a line, especially anus, vulva, armpits, hands and feet are obvious, palmar sac also see skin lesions, damage is clear erythema, clusters of blisters, scarring and erosion, trunk lesions It is fused into plaque, which causes natural regression, leaving with mild sputum changes and pigment changes. Later, it can be repeated in the same place, consciously itching and burning sensation, ultraviolet radiation, mechanical damage, infection, etc. can induce skin lesions. Three generations in the family have the disease.
Examine
Examination of recurrent linear acantholytic skin disease
Histopathology: The spines on the basal layer loosen to form fissures and blisters, which contain loose or patched acantholytic cells, most of which are still connected by residual intercellular bridges.
Diagnosis
Diagnosis and diagnosis of recurrent linear acantholytic dermatosis
The disease is similar to familial benign pemphigus in some aspects, all of which are recurrent vesicular damage and spine lysis, pathological and ultrastructural changes are similar, but the disease is unilateral linear arrangement, early onset, palmar It is considered to be a new disease.
