atypical measles syndrome
Introduction
Introduction to atypical measles syndrome Atypical measles syndrome (atypicalmeaslessyndrome) refers to the atypical morbidity caused by the decrease of antibody levels in the blood after 2 to 6 years of vaccination against measles vaccine, and the clinical manifestations of measles. It is distributed in winter and spring and is not contagious. basic knowledge The proportion of sickness: 0.004% - 0.006% Susceptible people: more common in teenagers Mode of infection: non-infectious Complications: pneumonia, pleural effusion, myocarditis
Cause
Atypical measles syndrome etiology
(1) Causes of the disease
The measles vaccine is inoculated due to the combination of measles virus antigen and circulating antibodies to form an immune complex.
(two) pathogenesis
The measles vaccine is used to obtain long-lasting immunity. When the measles virus is reinfected, the sensitized lymphocytes cause delayed allergic reaction to the components of the viral antigen and the host cells, which causes the disease. Some people think that the disease is caused by the measles virus. The antigen is combined with the circulating antibody to form an immune complex.
Prevention
Atypical measles syndrome prevention
There is no effective preventive measure for this disease in atypical measles syndrome. Early detection and early diagnosis are the key to prevention and treatment of this disease.
Complication
Atypical measles syndrome complications Complications, pneumonia, pleural effusion, myocarditis
Can be complicated by pneumonia, pleural effusion and lung lymphadenopathy, but also complicated by encephalitis, myocarditis and so on.
Symptom
Symptoms of atypical measles syndrome Common symptoms Spotted fever, high pleural effusion, lymphadenopathy, papules, myalgia, abdominal pain
Acute onset, high fever, headache, abdominal pain, myalgia and other general malaise, but no cough, runny nose and conjunctivitis symptoms, the onset of 2-3 days from the extremities, foot, ankle, wrist and wrinkles appear macules, pimples , phlegm, urticaria, blisters and other pleomorphic rashes, 3 to 5 days spread to the trunk, limbs, palmar, oral cavity, there are no spots, no Koplik spots, rash at the vaccination site is more obvious, rash 2 weeks subsided, can be complicated by pneumonia, pleural effusion and lung lymphadenopathy, can also be complicated by encephalitis, myocarditis and so on.
Examine
Examination of atypical measles syndrome
The total number of white blood cells decreased, lymphocytes or eosinophils increased, serum transaminase, acid dehydrogenase increased, serum measles antibody titers increased, and measles virus culture was negative.
Diagnosis
Diagnosis and diagnosis of atypical measles syndrome
According to the vaccination of measles vaccine 2 to 3 days, the above clinical manifestations are not difficult to diagnose.
