Symmetric keratosis erythematosus
Introduction
Introduction to symmetry progressive erythematization Progressive sympathetic erythematous keratosis (symmetricalprogressive erythrokeratoderma) is an autosomal dominant keratosis abnormal disease, which is mainly characterized by progressive erythematous keratosis of bilateral palmar, with obvious boundary and chronic course. basic knowledge The proportion of illness: 0.0025% Susceptible people: no special people Mode of infection: non-infectious Complications: papular urticaria
Cause
Symmetry of progressive erythematous keratosis
(1) Causes of the disease
It is an autosomal dominant keratinization abnormality.
(two) pathogenesis
The pathogenesis is still unclear.
Prevention
Symmetric progressive erythema keratosis prevention
There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.
Complication
Symmetric progressive erythematous keratosis complications Complications, papular urticaria
Concurrent palm and toe skin hyperkeratosis, papules.
Symptom
Symmetry progressive erythematous keratosis symptoms common symptoms hand and foot sweaty keratin thickening scaly erythema (border clear...
Infants can develop disease, start sweating in the hands and feet, skin lesions occur symmetrically in the palm of the hand, local keratin thickening, color flushing, sputum-like, clear surrounding, yellow-red, surface may have scaly scales, rash can gradually The back of the hands and feet, the extension of the extremities and the elbow joints, etc., occasionally the thighs, upper arms, shoulders, neck and face can also be affected, or can be irregularly distributed, or confined to one place, the hair follicles are keratinized, but no papules are formed. The redness is obvious in summer, and the keratinization and drying in winter is remarkable, and cracking can occur.
Examine
Symmetry of progressive erythematous keratosis
Histopathology: The layers of the epidermis were thickened, with the stratum corneum being the most prominent. The superficial dermis had telangiectasia and mild inflammatory cell infiltration.
Diagnosis
Diagnosis and differentiation of sympathetic progressive erythematous keratosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
1. Hair red pityriasis: slow, wide range, with follicular keratotic papules, especially the first and second sections of the dorsal side are particularly prominent, and there is a hibiscus-like feeling.
2. Verrucous keratosis: The lesion is most flattened keratinized papules, distributed on the dorsal side of the hands and feet, and sometimes arranged in a line.
