hibernoma
Introduction
Introduction to hibernating tumor Hibernoma (brownfattumor) is a benign tumor composed of brown fat cells. Brown fat is present in mammalian and human fetal stages and gradually decreases with age. The disease is extremely rare, mostly occurring in adults aged 20 to 50 years, without gender differences. basic knowledge The proportion of illness: 0.005% Susceptible people: no special people Mode of infection: non-infectious Complications: lipoma
Cause
Hibernoma
Cause:
Since hibernating tumors were recognized at the end of the last century, it accounted for 1.6% of benign fat tumors and 1.1% of all adipose tissue tumors in the AFIP file. Among the 170 cases of AFIP, most of the hibernomas occur in young people, with an average age of 38 years, 60% occurring between 20-40 years old, only 5% occurring in children aged 2-18 years, and 7% of patients are older than 60 years old. The proportion of males is slightly more.
Involved parts: The area where hibernating tumors occur is very extensive. The most common parts are the thighs, followed by the torso, upper limbs and head and neck. Mucin-like subtypes and spindle cell subtypes are as common in the posterior neck and shoulder as spindle cell lipomas, with less than 10% of cases occurring in the abdomen and thoracic cavity. The cause is still unknown.
Prevention
Hibernation tumor prevention
Precaution:
Prevention of this disease is the same as other malignant tumors, and tertiary prevention can be used.
1. Primary prevention is the cause of prevention: its goal is to prevent the occurrence of cancer. Its tasks include studying the causes and risk factors of various cancers, taking preventive measures against specific carcinogenic, cancer-promoting factors and pathogenic conditions in vitro and in vivo, such as chemical, physical, biological, etc., and adopting environmental protection, appropriate diet, and appropriateness for healthy organisms. Sports to promote physical and mental health.
2. Secondary prevention or preclinical prevention: The goal is to prevent the development of initial disease. This includes early detection of cancer, early diagnosis, and early treatment to prevent or slow the progression of the disease, and reverse to phase 0 as soon as possible.
3. Tertiary prevention is clinical (phase) prevention or rehabilitation prevention: its goal is to prevent the disease from worsening and disability. The task is to adopt multidisciplinary diagnosis (MDD) and treatment (MDT), correctly select the right and best treatment plan to fight cancer as soon as possible, try to promote recovery function and recovery, prolong life, improve quality of life, and even reintegrate into society.
Complication
Hibernation tumor complications Complications
There are usually no special complications.
Symptom
Hibernation tumor symptoms common symptoms cystic mass growth slow skin tenderness
Tumors occur in the scapular region, chest, neck, femoral, etc., often under the skin, occasionally reach muscle tissue, the boundary is clear, the diameter can reach 19cm (average 10cm), clinically benign, slowly increase, occasionally tender.
Examine
Hibernation tumor examination
Histopathology: The tumor tissue has a complete envelope, which is divided into numerous small leaves by the connective tissue. The tumor cells are large brown fat cells with a diameter of 20-50 m, polygonal, rich in cytoplasm, containing a large number of eosin particles, more vacuoles. Positive for fat staining, proved to have lipids, lipofuscin is seen between the cytoplasmic foam, the nucleus is small and round, centered or biased to one side, and the blood vessels in the tumor are abundant, and some mature mature fat cells are scattered.
Diagnosis
Diagnosis and diagnosis of hibernating tumor
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
1. Xanthoma: The tumor cells are small in size and often accompanied by other inflammatory cells and proliferating fibroblasts. The xanthoma giant cells are characteristic.
2. Granulous myoblastoma: no intact capsule, the tumor cells are arranged in a nest or bundle.
