subcutaneous lipogranuloma
Introduction
Introduction to subcutaneous fat granuloma Lipogranulomatosis subcutanca, also known as Rothamann-Makai syndrome, occurs in the subcutaneous tissues of the lower extremities and trunk of children and obese women. After a slow, prognosis is considered to be a subtype of Weber-Christian panniculitis, but not fever, lack of systemic symptoms. basic knowledge The proportion of illness: 0.001% Susceptible people: good for children and obese women Mode of infection: non-infectious Complications: sepsis
Cause
Causes of subcutaneous fat granuloma
(1) Causes of the disease
Although there may be trauma or vascular injury factors, the exact cause is not known.
(two) pathogenesis
The pathogenesis is still unclear.
Prevention
Subcutaneous fat granuloma prevention
Although there may be trauma or vascular injury factors, the exact cause is not known. It occurs in the subcutaneous tissues of the lower limbs and trunk of children and obese women. Therefore, it is impossible to prevent the etiology. For those who are obese, they should pay attention to controlling diet, especially the need to limit the intake of greasy food to reduce the risk of acquiring this disease. Early diagnosis and early treatment are also important for the prevention of complications.
Complication
Subcutaneous fat granuloma complications Complications sepsis
This disease is mainly caused by the destruction of skin integrity, so it can be caused by skin bacterial infection or fungal infection, usually secondary to low body, or long-term use of immunosuppressants and fungal infections such as nail fungus, such as concurrent bacteria Infection can have fever, skin swelling, ulceration and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Subcutaneous fat granuloma symptoms Common symptoms Skin adhesion subcutaneous nodules
Skin damage is a small number of subcutaneous nodules of varying sizes. It is as small as a bean, resembling an almond. It is hard at the beginning, often adheres to the skin, hides the skin under the skin or micro-lobe, has a slight pressure, and the surface color is normal or reddish. The nodules disappear without atrophy and depression, occasionally nodular liquefaction and rupture, discharge aseptic cheese necrotic oil-like substances, nodules often appear one after another, continuous in obese women or children, skin lesions scattered Limbs, rich fat in the trunk, more common in the buttocks and femoral extension.
Examine
Subcutaneous fat granuloma examination
Histopathology: Invasive inflammation of the initial fat lobule with neutral polynuclear cells, degeneration and necrosis of fat cells, macrophages appear later, phagocytosis of fat granules is a cluster of granuloma, which contains tissue cells, lymphocytes, and fat cells. Finally, replaced by fiber, cystic-like lipid degeneration, calcium salt deposition and vasculitis changes, thickening of the intima, thinning of the vascular lumen, cell infiltration around.
Diagnosis
Diagnosis and diagnosis of subcutaneous fat granuloma
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
According to its clinical characteristics, it can be differentiated from hard erythema, nodular erythema, nodular vasculitis.
