Skin penetrating follicular and perifollicular keratosis
Introduction
Introduction of skin penetration hair follicles and follicular keratosis Skin penetration hair follicles and keratosis follicularisetparafollicularisincutempenetrans, also known as dermal perforating hair follicles and hyperkeratosis follicularisetparafollicularisincutempenetrans, perforkeratosispenetrans, hair follicles and parakeratosis (hyperkeratosisfollicularisetparafollicularis), this disease is rare, first described by Kyrle in 1916. It is characterized by conical keratotic papules formed by hyperkeratosis of follicular or non-follicular skin, nodules, dents after keratin peeling, and good limbs. basic knowledge Sickness ratio: 0.001%-0.01% Susceptible people: more common in 20 to 60 years old Mode of infection: non-infectious Complications: Diabetes
Cause
Penetration of skin follicles and follicular keratosis
The cause is unknown, may have a family history, most believe that the disease is a hereditary skin disease, may be autosomal recessive, some people think that may be related to diabetes and chronic renal insufficiency or infection factors, there are also considered abnormal metabolism with vitamin A related.
Pathogenesis
The pathogenesis is still unclear, and some believe that it may be related to autosomal recessive inheritance, diabetes and chronic renal insufficiency or to infectious factors.
Prevention
Skin penetration hair follicle and hair follicle keratosis prevention
1. It is recommended to take a bath with loofah, bath salt or scrub, but don't take it too often, use too much skin, it is recommended once a month.
2. It is recommended to wash the skin when washing, remove excess keratin, apply BB oil or olive oil after bathing, apply moisturizer, all year round.
3. It is recommended to use A-acid products such as Divi Paste to improve keratin.
4. It is best to treat early, because in the early stage of the disease, not only the rash is easy to get rid of some, but generally there is no obvious pigmentation. And if the onset time is too long, not only will the rash become deep-rooted, the treatment will be much more difficult, and there will be residual pigmentation that is difficult to subside!
5. Do not squeeze the rash often, because after the rash is squeezed out, it is easy to leave small scars.
Complication
Skin penetration hair follicles and follicular keratosis complications Complications diabetes
The disease is often accompanied by diabetes and liver and kidney disease.
Symptom
Skin penetration hair follicles and hair follicles keratosis symptoms common symptoms pores thick horn tying papule nodules blush
Slow onset, generally no symptoms, more common in 20 to 60 years old, skin lesions occur in the limbs, the basic damage is follicular keratotic papules, the center has a horn plug, remove the angle plug visible pit, damage is skin color or light brown, There are blush around, sometimes the skin lesions can be merged into sputum plaques, palmar, mucous membranes are generally not affected, this disease is often accompanied by diabetes and liver and kidney diseases, such as diabetes and liver and kidney disease are controlled, the disease can be reduced or self-resolved .
Examine
Examination of skin penetration hair follicles and follicular keratosis
Laboratory indicators of related diseases such as blood sugar, increased urine sugar and so on.
Histopathology: The lesion is a highly keratinized and partially parakeratotic horny plug embedded in the epidermis. The keratinized or incompletely keratinized material extends to the epidermis of the epithelial invagination to compress the epidermis and invade from the epidermal rupture. In the upper part of the dermis, the horny plug has keratinized edges and basophilic debris. The depressed epidermis vacuoles and partial keratinization penetrate into the dermis, showing a granulomatous reaction composed of inflammatory cells and foreign body giant cells.
Diagnosis
Diagnosis and differentiation of skin penetrating hair follicles and follicular keratosis
diagnosis
According to the horny plug papules, nodules or plaques, after the angle plug is removed, there are pits and other features, and the pathology is easy to diagnose.
Differential diagnosis
Should be identified with the following diseases:
1. Puncture folliculitis is more common in young people, all of which are follicular keratopes, not in the vicinity of hair follicles, without fusion. The hair follicles contain corrugated or hair follicle stumps, hair piercing the epidermis and causing perforation. Sex fragments and inflammatory cells are discharged into the hair follicles.
2. The puncture-type elastic fiber disease has less keratotic papules, and the clusters are arranged in a ring shape; it occurs in the neck, frontal, facial or upper limbs, and the histopathology is mainly the superficial dermis, especially the elastic fibers in the nipple. Increased, thickened and excreted through the epidermis, the upper epidermis has a narrow tube, and the pipeline contains basophilic debris and eosinophilic elastic fibers discharged into the pipeline.
3. Reactive penetrating collagen disease is often associated with trauma, mostly in infants or children, the initial damage is needle-sized papules, showing skin color, and when the papules develop to 4-6 mm, the central part forms umbilical depression, which is more common in the back of the hand. Forearms, elbows, knees, etc., skin lesions can resolve spontaneously within 6 to 8 weeks, combined with pathology can be distinguished.
