Skin T cell lymphoid hyperplasia
Introduction
Introduction to cutaneous T-cell lymphoid hyperplasia Skin T-cell lymphoid hyperplasia (band-like and perivascular pattern) can be idiopathic or photoallergic, drugs (usually anti-epileptic drugs, but there are many other drugs), contact dermatitis As a result, the patient may have one of two types of lesions, one with extensive scaly erythema and thicker plaques. Another type of lesion is more papular or nodular lesions, clinically similar to B-cell lymphoid hyperplasia. Usually idiopathic. basic knowledge The proportion of illness: the incidence rate is about 0.007%-0.008% Susceptible people: more common in young women Mode of infection: non-infectious Complications: sepsis
Cause
Etiology of cutaneous T-cell lymphoid hyperplasia
The main factor (65%):
Skin T-cell lymphoid hyperplasia (banded and perivascular) can be idiopathic or photoallergic (formerly known as actinic reticulosis, now known as chronic actinic dermatitis), drugs (usually resistant) Epilepsy drugs, but there are many other drugs), contact dermatitis (so-called lymphoma-like contact dermatitis).
Secondary factor (35%):
Followed by aphids or arthropod bites, some authors consider Jessner lymphocyte infiltration into this group, while others believe that the disease has nothing to do with lymphoid hyperplasia.
Pathogenesis
The pathogenesis is still unclear.
Prevention
Skin T cell lymphoid proliferative prevention
The disease is related to the use of certain drugs, such as anti-epileptic drugs, and ultraviolet light. Therefore, clinical prevention should be carried out according to the cause, avoiding the use of anti-epileptic drugs, avoiding sun exposure and reducing the risk of acquiring the disease. For patients who have obtained this disease, especially those with bacterial and fungal infections, they should be actively treated to reduce the occurrence of complications.
Complication
Complications of cutaneous T-cell lymphoid hyperplasia Complications sepsis
The disease is usually associated with medication and is currently considered to be directly linked to allergic injury. This disease can cause skin rupture, so it can cause skin bacterial infection or fungal infection due to the destruction of skin integrity, usually secondary to low constitution, or long-term use of immunosuppressants and fungal infections such as onychomycosis, such as Concurrent bacterial infections may have symptoms such as fever, swelling of the skin, ulceration, and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Symptoms of skin T-cell lymphoid hyperplasia Common symptoms Nodular papules scales
The patient may have one of two types of damage, one that is similar to mycosis, a erythema with extensive scaly, and a thicker plaque, often caused by drugs, and the other is more The papular or nodular lesions, clinically similar to B-cell lymphoid hyperplasia, usually idiopathic, rarely caused by drugs, damage without symptoms, smooth surface, red to purple, the epidermis is not tired, no scales, Young women are more common after the skin lesions have subsided.
Examine
Examination of cutaneous T-cell lymphoid hyperplasia
Histopathology: The first type of lesion is a banded infiltration of the dermis, sometimes with epidermal, no real epidermal junction, infiltration consisting of a mixture of small lymphocytes and some eosinophils, and the second lesion is around the sleeve-like blood vessels. Infiltration of small lymphocytes, infiltration of inflammatory cells at the undirected epidermal or true epidermal junction.
Diagnosis
Diagnosis and differentiation of skin T-cell lymphoid hyperplasia
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
The disease should be differentiated from papular urticaria and skin tuberculosis. Papular urticaria, also known as urticaria, baby moss or urticaria, acute simple pruritus, is a common allergic skin disease in infants and young children. The clinical features are scattered, slightly harder, papules with vesicles on the top. There is a spindle-shaped blush around the circumference, consciously itching. Pathological examination of skin tuberculosis showed granulomatous lesions.
