Plummer-Vinson syndrome
Introduction
Introduction to Plummer-Vinson Syndrome Plummer-Vinson syndrome, also known as Paterson-Kelly syndrome or iron deficiency dysphagia, is mainly characterized by iron deficiency anemia, dysphagia and glossitis. It occurs in white women aged 30-50 years, and males are rare. Chinese are rare. basic knowledge Sickness ratio: 0.05% Susceptible people: white women who are 30 to 50 years old Mode of infection: non-infectious Complications: esophageal cancer
Cause
Causes of Plummer-Vinson Syndrome
Iron deficiency is the most basic cause of intrinsic cerebral palsy, but it is more common in ectopic eclipse patients. However, patients with iron deficiency anemia do not have difficulty swallowing. Therefore, iron deficiency is not the only reason, and may also be related to B vitamin deficiency, physique and ethnicity. Related to factors such as family.
Mainly for the pharynx and upper esophageal mucosa atrophy, under the muscle atrophy and degeneration, there are mucosal sepals.
Prevention
Plummer-Vinson Syndrome Prevention
Pay attention to rest, work and rest, life in an orderly manner, and maintaining an optimistic, positive and upward attitude towards life can be of great help in preventing diseases.
Complication
Plummer-Vinson syndrome complications Complications Esophageal cancer
Easy to develop both pharyngeal and upper esophageal cancer, the prognosis is mostly good, and individual cases can be delayed.
Symptom
Symptoms of Plummer-Vinson Syndrome Common Symptoms Pharyngeal Foreign Body Swallow Difficulty Tongue Deficiency Iron Deficiency Heart Shaped Key (toe) Hair Loss Loss of Appetite and Poor Anemia
The main clinical manifestations are dysphagia, pharyngeal foreign body sensation, dysphagia is intermittent, without pain, often develops persistent, more common iron deficiency anemia, such as loss of appetite, fatigue, palpitations, pale, spoon-like fingers ( Toe) and hair loss, often accompanied by angular cheilitis, glossitis, smooth tongue, atrophy, nipple disappeared, most patients with X-ray and esophagoscopy found in the lower part of the throat, the upper part of the esophagus has a diaphragm type mucosa, almost all laboratory tests Iron deficiency anemia, serum iron concentration is significantly reduced, and some have pernicious anemia.
1. There is iron deficiency anemia, difficulty in swallowing, clinical manifestations of glossitis.
2. Esophageal barium meal or esophagoscopy has a diaphragm-like mucosal septum at the upper end of the lower esophagus.
Examine
Plummer-Vinson Syndrome
Laboratory and auxiliary inspection:
Blood routine: iron deficiency small cell hypochromic anemia.
X-ray examination: If you suspect sputum, you need to rely on fluorescent film examination, often found in the anterior wall of the upper esophageal side of the eccentricity, the width of less than 2mm.
Gastroscopy: A smooth, colored septum-like hole can be found with an eccentric opening, located below the level of the pharyngeal muscle, and a thin film.
Diagnosis
Diagnostic identification of Plummer-Vinson syndrome
Generally diagnosed, no need to identify.
