Spleen-Liver Syndrome
Introduction
Introduction to spleen-hepatic syndrome Spleen-Liver Syndrome refers to a group of symptoms of splenomegaly, anemia, cirrhosis, also known as thrombophlebitis splenomegaly syndrome, splenic anemia, congestive splenomegaly syndrome, chronic congestive spleen Swelling, liver and spleen fibrosis, fibrotic congestive splenomegaly syndrome. Banti was described in the first year of 1883, so it is also known as Banti syndrome. At that time, the spleen was considered to be the primary site of the disease, and the intrinsic part was divided into an anemia phase, a transition phase and a terminal liver cirrhosis phase according to clinical symptoms. Many scholars later opposed Banti's disease as an independent disease. It is currently believed that this disease is caused by repeated inflammation of the portal vein, resulting in portal vein, splenic vein thrombosis and occlusion or cirrhosis. Therefore, it is advisable to abandon this diagnostic name. basic knowledge Sickness ratio: 0.0001% Susceptible population: patients are mostly under 35 years old Mode of infection: non-infectious Complications: anemia, gastrointestinal bleeding, indigestion
Cause
Cause of spleen-hepatic syndrome
The pathological changes were mainly liver, splenomegaly, thickened cysts and harder texture, pale gray-red, histological fibrosis, hepatic sinus dilatation, transparent degeneration of Malipighian bodies, hemorrhage around arteries, arterioles Around the iron deposits small nodules, the spleen is more obvious swelling, the degree of swelling is directly proportional to the hyperfunction of the spleen, but there is no obvious relationship with the length of the disease, due to fibrous tissue hyperplasia, the longer the course, the harder the spleen.
Prevention
Spleen-hepatic syndrome prevention
This disease should be taken to prevent liver disease and vascular inflammation.
Complication
Spleen-hepatic syndrome complications Complications anemia, digestive tract bleeding, indigestion
The disease is easy to be complicated by anemia, gastrointestinal bleeding, indigestion and other diseases.
Symptom
Symptoms of spleen-hepatic syndrome common symptoms liver function impaired nausea jaundice portal hypertension diarrhea nose yellow or brown indigestion viscera dysfunction anorexia
Most patients are under 35 years old, most of the cases are insidious. The main clinical manifestations are obvious spleen (mostly severe) swelling, anemia and/or portal hypertension, and good liver function, few symptoms, fatigue, indigestion Symptoms such as bloating, anorexia, nausea, diarrhea, etc., there are sudden gastrointestinal bleeding, occasionally mild jaundice and skin pigmentation, the liver is mostly mild swelling.
1. The spleen is obviously swollen.
2. Complete blood cell reduction (bone marrow shows nucleated cell maturation is blocked) and portal hypertension manifestations and liver function damage is more severe.
3. Need to exclude other major spleen diseases, such as post-hepatitis cirrhosis, chronic myeloid leukemia, kala-azar, Niemann-Pick syndrome, subacute bacterial endocarditis.
Examine
Spleen-hepatic syndrome test
1. Laboratory examination sees red blood cells, white blood cells, hemoglobin and platelet counts, complete blood cell reduction, bone marrow shows nucleated cell proliferation, mature obstacles, serum iron can be reduced, total iron binding capacity can be increased, liver function can have different degrees damage.
2. X-ray examination may have esophageal or gastric varices.
Diagnosis
Diagnosis and differentiation of spleen-hepatic syndrome
Attention should be distinguished from diseases such as hepatitis, cirrhosis, chronic myeloid leukemia, kala-azar, Niemann syndrome, and subacute bacterial endocarditis.
