Simple pulmonary eosinophilia
Introduction
Introduction to simple pulmonary eosinophilia Simple pulmonary eosinophilia (simplepulmonaryeosinophilia) was first reported by Loffler in 1932, so it is also known as Lofflers syndrome. It is characterized by mild systemic symptoms, a transient lung shadow on the X-ray, and blood eosinophilia. The course of disease is 2 to 4 weeks, also known as acute pulmonary eosinophilia (acutepulmonaryeosinophilia). Patients may have individuals or families. allergies. basic knowledge The proportion of illness: 0.0002% Susceptible people: no specific people Mode of infection: non-infectious complication:
Cause
Causes of simple pulmonary eosinophilia
(1) Causes of the disease
There are many causes, mainly parasitic infections and drug-induced allergies. Allergies to larvae of mites occur more than 2 weeks after infection. Aphid allergens can cause positive skin reactions, in addition to hookworms, roundworms, and worms. Trichomonas, whipworms, liver flukes of amoeba, and Schistosoma japonicum can also produce the same response.
Drugs such as aspirin, various sulfa preparations, nitrofurantoin, penicillin, methotrexate can cause allergic reactions, as well as allergies to inhaled pollen and fungal spores.
Recently, there have been reports of this disease due to nickel. This disease is associated with type I allergy, and type III allergic reactions can also participate.
(two) pathogenesis
Mainly for the temporary allergic reaction in the lungs, the alveoli are filled with exudate, a large number of eosinophils and foreign body macrophages, rarely involving blood vessels, and there are white blood cells around the blood vessels.
Prevention
Simple pulmonary eosinophilia prevention
There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.
Complication
Complications of simple pulmonary eosinophilia Complication
It may weaken the patient. The gradual increase in symptoms is markedly different from the acute onset of influenza and adenovirus respiratory infections. 5%-10% of patients can further develop into tracheobronchitis or pneumonia, which has a certain relationship with the patient's age. At this stage, the original clinical manifestations still exist, the cough is more serious, the whiteness is less white, and occasionally bloody in the sputum. The patient's body temperature is usually between 37.8 and 38.5 °C with stomach cold, but true chills (such as patients with pneumococcal pneumonia) are rare.
Symptom
Symptoms of simple pulmonary eosinophilia Common symptoms Lemon color sputum hemoptysis with fever chest tightness hernia chest tightness eosinophilia
The disease can be asymptomatic, only found on X-ray examination; if symptoms are also very mild, the most common symptoms are cough, a small amount of sticky or a small amount of lemon sputum, occasional blood stasis, sputum contains eosinophils Cells, in addition to headache, fatigue, upper respiratory catarrh symptoms, night sweats, chest pain, etc., generally do not have fever, if there is low fever, occasionally high fever and wheezing, often return to normal within 1 to 2 days, clinical examination may be no Any signs, rarely heard a small amount of dry and wet voice, even can be diagnosed with dullness, symptoms and signs mostly disappear in the short term, rarely more than two weeks.
Examine
Examination of simple pulmonary eosinophilia
The total number of white blood cells is normal or mild to moderately elevated, the proportion of blood eosinophils is increased to 10% to 70%, eosinophils can be increased in sputum and bronchoalveolar lavage (BALF), blood IgE, IgM is high. Under normal values.
Chest X-ray showed unilateral or bilateral lung infiltration shadows, blurred edges were small or large non-segmental distribution, lesions disappeared in 6 to 12 days; or migratory lesions, reduced or disappeared within 24 hours At the same time, new lesions appeared elsewhere, and individual pericardial or pleural effusions were reported separately, but no cases of empty holes were found.
Diagnosis
Diagnosis and diagnosis of simple pulmonary eosinophilia
Mainly according to the symptoms, X-ray chest radiographs have a transient migratory shadow, elevated eosinophils in the blood, short course of disease can be self-healing and other characteristics to make a diagnosis, caused by aphid infection, 2 to 3 after symptoms appear At the time of the month, eggs can be found in the feces.
The disease should be differentiated from viral pneumonia, mycoplasma pneumonia, bacterial pneumonia and pulmonary infarction. The latter's blood eosinophils do not increase. If the symptoms persist, the connective tissue disease should be excluded.
