CD30-positive cutaneous T-cell lymphoma

Introduction

Introduction to CD30 positive skin T cell lymphoma CD30 positive cutaneous Tcell lymphoma (CD30) is also known as primary CD30-positive cutaneous T-cell lymphoma. It is a single or localized skin lesion, prone to ulceration (50%) and natural regression (25%), rare in children. More men than women. basic knowledge The proportion of illness: this disease is rare, the incidence rate is about 0.004%-0.006% Susceptible people: seen in children Mode of infection: non-infectious complication:

Cause

CD30 positive skin T cell lymphoma etiology

The cause is not clear.

Prevention

CD30 positive skin T cell lymphoma prevention

There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Complication

CD30 positive skin T cell lymphoma complications Complication

A subtype of CD30+ cutaneous T-cell tumor is an ulcerative skin nodule with recurrence and regression, similar to gangrenous pyoderma or sickle tumor. This type, formerly known as degenerative atypical histiocytosis, is now considered to be a cutaneous T-cell lymphoma. About 30% of cases can develop into extra-cutaneous tumors.

Symptom

CD30-positive skin T-cell lymphoma symptoms Common symptoms Histiocytosis nodules

The damage is usually solid, red to purple tumors, up to 10cm in diameter, no predilection, often recurring on the skin, but rare in the skin or lymph nodes, local lymph node involvement does not indicate poor prognosis, CD30 + skin T cells A subtype of the tumor, a relapsing and regressing ulcerative skin nodule, similar to gangrenous pyoderma or sputum tumor, a form previously known as degenerative atypical histiocytosis, now considered a skin T Cell lymphoma.

Examine

Examination of CD30 positive skin T cell lymphoma

Histopathology: dense non-pro-epidermal dermal infiltration, atypical nuclei, 1 to several distinct nucleoli, rich in cytoplasm, this malignant cell can be further divided into anaplastic, polymorphic and immunoblastic However, this distinction may be difficult and the value in treatment and prognosis is undetermined.

Diagnosis

Diagnosis and diagnosis of CD30 positive skin T cell lymphoma

According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.

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