Milk-Alkali syndrome
Introduction
Introduction to Milk-Alkali Syndrome Milk-Alkali Syndrome refers to a group of clinical patients with hypercalcemia, alkalosis and varying degrees of renal dysfunction caused by long-term consumption of large amounts of milk or calcium and taking a large amount of absorbable alkali. Symptoms, which used to occur in the medical treatment of patients with peptic ulcer in the past, are now rare due to improvements in treatment options, such as taking insoluble alkaline drugs. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious Complications: peptic ulcer renal failure
Cause
Causes of Milk-Alkali Syndrome
Cause:
Long-term consumption of calcium-rich, phosphorus-rich milk and the use of a large number of alkaline agents that are easily absorbed by the intestine are the cause of the intrinsic. People with frequent vomiting and original kidney disease are more likely to induce and aggravate the intrinsic, milk is rich in calcium and phosphorus. Long-term drinking will inevitably lead to an increase in calcium and phosphorus in the body, and often take a large amount of easily absorbed alkali agents, causing alkalosis, promoting intestinal calcium absorption, causing calcium and phosphorus ions in the body to settle in soft tissues, mainly in the kidneys. And the eyes, other skin, blood vessels, lungs, brain, etc. can also be deposited, causing damage to the structure and function of the corresponding tissues and organs.
Prevention
Milk-Alkali Syndrome Prevention
Long-term consumption of calcium- and phosphorus-rich milk and the use of a large number of alkaline agents that are easily absorbed by the intestine are the cause of the intrinsic. People with frequent vomiting and existing kidney disease are more likely to induce and aggravate the intrinsic. Milk is rich in calcium and phosphorus, and long-term drinking will inevitably lead to an increase in calcium and phosphorus in the body. Because it often takes a lot of easily absorbed alkaline agents, causing alkalosis, promoting intestinal calcium absorption, causing calcium and phosphorus ions in the body to settle in soft tissues, mainly in the kidneys and eyes, other such as skin, blood vessels, lungs, brain, etc. It can also deposit, causing damage to the structure and function of the corresponding tissues and organs.
Complication
Complications of Milk-Alkali syndrome Complications, peptic ulcer, renal failure
Peptic ulcer, urinary tract infection, renal failure and so on.
1. Peptic ulcer mainly refers to chronic ulcers that occur in the stomach and duodenum. It can also occur in the lower part of the esophagus, around the anastomosis of the stomach and jejunum, and in the MECKEL chamber containing the ectopic gastric mucosa. The formation of these ulcers is related to the digestion of gastric acid and pepsin, so it is called peptic ulcer.
2. The pathological state in which part or all of the kidney function is lost. According to the rapid onset of the attack, it is divided into acute and chronic.
Symptom
Symptoms of Milk-Alkali Syndrome Common Symptoms Nocturia Increases Hematuria Metabolic Alkalosis
1. There is a large amount of long-term consumption of milk and the history of taking basic drugs.
2. The serum calcium level is higher than 2.56mmol/L.
3. Metabolic alkalosis, blood carbon dioxide binding capacity and pH are higher than normal.
4. There are renal dysfunction, such as increased nocturia, low urine weight, blood urea nitrogen, creatinine increased.
5. There is a manifestation of soft tissue calcium deposition.
6. The condition can be improved after stopping the milk and alkali agent.
Examine
Examination of Milk-Alkali syndrome
Clinical physical examination: After a week of eating milk and taking a lot of easily absorbed alkalinity agents, but no eye involvement, the symptoms often disappeared after stopping the milk and alkali agents, and the kidney function was also restored. Banded keratopathy and membranous granules may appear. Calcium may also appear in the soft tissues of the whole body. Symptoms may gradually disappear after stopping the milk and alkali agents, and the renal function recovery is slow, but it can be completely recovered, but the soft tissue calcium is extensive. Severe, impaired renal function, blood calcium can be reduced to normal after stopping the milk and alkaline agents, but renal insufficiency can not fully recover.
Laboratory examination: biochemical examination of serum calcium increased, more than 2.56mmol / l.
Diagnosis
Diagnosis and identification of Milk-Alkali syndrome
Can be diagnosed based on clinical symptoms and laboratory tests.
It needs to be differentiated from hypercalcemia or calcareous disease caused by primary hyperparathyroidism, vitamin D poisoning, sarcoidosis, malignant tumor metastasis.
