subacute nodular migratory panniculitis
Introduction
Introduction to subacute nodular migratory panniculitis Subacute nodular migratory panniculitis (subacutenodularmigratorypanniculitis) is a rare subcutaneous panniculitis, also known as nodular migratory panniculitis, often in the lower part of the lower leg, the skin lesions are pale yellow or reddish Subcutaneous nodules, merging each other, hard as a wooden board, the center subsides, and travels around in a centrifugal shape. The course of the disease is delayed for several months or years. basic knowledge The proportion of illness: 0.001% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
The cause of subacute nodular migratory panniculitis
(1) Causes of the disease
The cause is not known and may be related to upper respiratory tract infection or tonsillitis, trauma, and arthritis.
(two) pathogenesis
The pathogenesis is still unclear.
Prevention
Subacute nodular migratory panniculitis prevention
Remove the lesions, control the infection, and keep warm.
Complication
Subacute nodular migratory panniculitis complications Complication
Generally no special complications.
Symptom
Subacute nodular migratory panniculitis symptoms common symptoms panniculitis nodules
The lesion is initially a painless solid nodule with a diameter of about 1 to 3 cm. It can be fused or become a large piece. It is an irregular shaped hard block. It is hard like a wooden board. It has a scleroderma-like panniculitis and a bright red edge. The center is reddish or pale yellow. As the disease progresses, the center subsides and expands to the periphery. The new rash continues to occur. The course of the disease can be delayed for several months or years. It occurs in adult women and is often found in the internal iliac crest. After extending to the side of the calf and front of the calf, often unilateral involvement, lack of self-conscious symptoms and systemic reactions.
According to clinical manifestations, the characteristics of skin lesions, erythrocyte sedimentation rate, rheumatoid factor can be positive, anti-streptococcal lysin O titer increased, histopathological features can be diagnosed.
Examine
Subacute nodular migratory panniculitis
The erythrocyte sedimentation rate is accelerated, the rheumatoid factor can be positive, and the anti-streptococcal lysin O titer is increased.
Histopathology: inflammatory cell infiltration of subcutaneous fat lobules, tissue cells, lymphocytes, plasma cells, foreign body giant cells infiltration degree, fat septal capillary vasculitis, endothelial hyperplasia, luminal stenosis and collagen fibrosis.
Diagnosis
Diagnosis and diagnosis of subacute nodular migratory panniculitis
1. The incidence of nodular erythema is more urgent, involving the anterior part of the calf, the inflammation of the lesion is significant, the pain is obvious, and more with systemic symptoms.
2. The incidence of intractable erythema is slow, the lesions are purple-red nodules, distributed in the flexor of the calf, can be ulcerated, scars are formed after healing, and histopathological changes show tuberculosis.
