Claramine poisoning
Introduction
Introduction to colamin poisoning Coramine, a lobeline, is widely used in pediatrics and can cause poisoning due to overdose or multiple injections of large doses. Lobelia, stalk and its seeds all contain scallions, and excessive oral administration can also cause poisoning. This drug directly excites the brain-storing center and stimulates the carotid chemosensory reflex excitatory respiratory center. basic knowledge Sickness ratio: 0.05% Susceptible people: good for children Mode of infection: non-infectious Complications: respiratory failure
Cause
Cause of venom poisoning
Cause:
Poisoning due to excessive dose or multiple injections of large doses of these drugs, lobelia, stalk and its seeds all contain sylvestre, and excessive oral administration can also cause poisoning. This medicine directly stimulates the brain and stimulates the brain. Carotid body chemoreceptor reflex excitatory respiratory center.
Prevention
Kelamin poisoning prevention
The key to prevention is not to abuse such drugs, and to educate children not to eat lobelia, stalks and their seeds. Reasonable dietary habits: Maintain a light diet. Eat more fresh vegetables. Such as green vegetables, radishes, etc. Should eat less meals. Fasting fat meat and animal offal, do not eat spicy onions, peppers, coffee, etc. Eat less refined sugar, honey, fruit candy, cakes, etc. Strengthen nutrition and use foods that are easy to digest, contain enough calories, protein and vitamins. Such as porridge, milk, soft rice, soy milk, eggs, lean meat, fresh vegetables and fruits rich in vitamins A, B, C. These foods can enhance the body's resistance.
Complication
Coma toxic complications Complications, respiratory failure
Due to convulsions or excessive excitement in the respiratory center, it is followed by a state of inhibition, eventually to respiratory failure.
Symptom
Symptoms of venom poisoning common symptoms dyspnea respiratory failure nausea convulsion diarrhea tremor convulsion coma urinary tract burning sensation
Poisoning sick children may have nausea, vomiting, headache, dizziness, paresthesia, sweating, coughing, deepening of breathing, speeding up, even breathing difficulties, tachycardia, irregular heartbeat, dilated pupils, slow response to light and disappear, and See muscle tremors and convulsions, insanity, convulsions, coma, blood pressure and hypothermia, etc., asparagus poisoning often has diarrhea, abdominal pain and urinary tract burning sensation, severe poisoning, due to convulsions or excessive excitement of the respiratory center, followed by inhibition, End to respiratory failure.
Examine
Examination of corona poisoning
An excessive poisoning test for liver function and kidney function, patients with longer poisoning time should check the ECG regularly.
Diagnosis
Diagnosis and identification of colamin poisoning
diagnosis
It can be diagnosed based on clinical symptoms and laboratory data.
Differential diagnosis
Organophosphorus poisoning:
When the organophosphate enters the human body, the phosphate ester is tightly bound to the cholinesterase active moiety to form a phosphorylcholinesterase, which loses its ability to hydrolyze acetylcholine, resulting in excessive accumulation of acetylcholine released by the cholinergic nerve. Causes cholinergic nerves and some central nervous system hyperexcitability, and then into inhibition and failure, resulting in symptoms of poisoning.
The patient's exposure to poison or swallowing organophosphate insecticides is one of the important criteria for determining the diagnosis. If the patient's stomach contents, respiratory secretions, and skin, clothing, etc., smell the organic phosphate ester, special garlic. Smelly smell, helpful for diagnosis.
Symptoms of poisoning include:
Muscarin-like manifestations: increased smooth muscle tendon and glandular secretion such as salivation, nausea, vomiting, abdominal pain, excessive sweating, increased bronchospasm and secretions, and severe pulmonary edema.
Nicotinic-like manifestations: Acetylcholine accumulates excessively in the striated muscle neuromuscular junction, muscle fibrillation, and even muscular tonic spasm, respiratory muscle paralysis.
Central nervous system manifestations: headache, dizziness, fatigue, ataxia, irritability, paralysis, convulsions and coma.
