acute abdominal-hyperlipidemia syndrome

Introduction

Introduction to acute abdominal-hyperlipidemia syndrome Acute Abdomen-Hyperlipemia Syndrome is also known as familial hyperlipoprotein blood type I, familial hyperchymitis, primary familial hyperlipidemia, hepatosplenomegaly Sedimentation, hypercholesterolemia, yellow lipoma, idiopathic lipidosis, hypercholesterolemia, lipomatosis, idiopathic lipidosis, and acute abdomen-hyperlipidemia syndrome. In 1932, it was first reported by Burger and Grutz, so it was also called the Burger-Grutz syndrome. It is a familial autosomal recessive hereditary disease. Clinically rare. basic knowledge The proportion of illness: 0.020% Susceptible people: no specific population Mode of infection: non-infectious Complications: pancreatitis

Cause

The cause of acute abdominal-hyperlipidemia syndrome

Pathologically, skin yellow tumors can be seen, and foam cells can be seen in tissues rich in reticulocytes (such as bone marrow, liver, and spleen), and the pancreas has inflammatory pathological changes.

Prevention

Acute abdominal-hyperlipidemia prevention

1. Adjust a reasonable diet to reduce the intake of saturated fatty acids and cholesterol.

2. Adjust life and work styles Actively participate in sports activities, avoid sedentary, and control weight. Smoking cessation is limited to alcohol.

3. Patients with a family history of coronary heart disease, diabetes, and primary hyperlipidemia should be regularly examined for blood lipids, blood sugar, and liver function.

4. Men over 40 years of age, menopausal women should be regularly checked for blood lipids every year.

5. In order to be able to detect hyperlipidemia in an early and timely manner, it is recommended that all adults over the age of 20 should regularly check plasma total cholesterol levels. Plasma triglyceride levels should be measured in all patients with pancreatitis.

Complication

Acute abdominal-hyperlipidemia syndrome complications Complications pancreatitis

Hyperlipidemia, pancreatitis, abnormal liver function, abnormal blood supply to the brain, kidney disease, etc.

Symptom

Symptoms of acute abdominal-hyperlipidemia syndrome Common symptoms Abdominal pain Hepatosplenomegaly Yellow nodules Nausea Abdominal discomfort Abdominal peritoneal irritation

Often in the onset of childhood, both sexes can be affected, can be induced when eating fat, manifested as upper abdominal discomfort, anorexia, abdominal pain, more nausea, vomiting, abdominal pain can be associated with fever, upper abdominal tenderness, pancreatitis and Peritoneal irritation, hepatosplenomegaly, spleen area without tenderness, about 30% of patients in the body (including mucosa) visible yellow tumor, that is, on the basis of erythema with yellow nodules, after the onset of yellow tumor in a few weeks The interior fades and even disappears completely.

Examine

Examination of acute abdominal-hyperlipidemia syndrome

The patient's plasma was placed in the upper layer at 4 °C and was white for type I hyperlipoproteinemia. Lipoprotein analysis showed: very low density lipoprotein (VLDL), low density lipoprotein (LDL), high density lipoprotein (HDL). Normal or decreased, cholesterol increased, triglyceride increased, white blood cells increased at the time of onset, liver function and glucose tolerance test were normal.

Diagnosis

Diagnosis and diagnosis of acute abdominal-hyperlipidemia syndrome

diagnosis

According to the clinical manifestations, after the intake of fat, induced symptoms such as upper abdominal pain, pancreatitis and other symptoms of skin yellow tumor, combined with high blood lipids can be diagnosed.

Differential diagnosis

It is distinguished from dietary hyperlipidemia such as diet, hypothyroidism, diabetes, kidney disease, biliary obstruction, and biliary cirrhosis.

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