Meningiosarcoma
Introduction
Introduction to meningeal sarcoma Meningosarcoma is one of the rare malignant tumors found in the brain and has a sarcoma morphology. More common in children, the course of disease is short, postoperative recurrence, and distant metastasis such as lung and bone can occur. basic knowledge The proportion of illness: 0.003% Susceptible people: more common in children Mode of infection: non-infectious Complications: intracranial hemorrhage
Cause
The cause of meningosarcoma
Pathogenesis:
Meningeal sarcoma is divided into primary and secondary types. Primary meningeal sarcoma can be divided into two types: single hair and meningosarcoma. The single hair style is more like a mass, and it can also be flat, transfibrosarcoma. More common, but also for spindle cells or polymorphic cell types, rapid growth, rich blood supply, meningioma is mostly from the dura mater or pia mater, if it occurs in the brain around the blood vessels of the pia mater, more than the dura mater Adhesive and located in the white matter of the brain, the tumor often has hemorrhage, necrosis or cystic change, the texture is crisp, the boundary is unclear, and the brain tissue around the tumor is infiltrated. Under the microscope, the tumor tissue infiltrates into the brain tissue, and the surrounding glial hyperplasia; Fibrous, fusiform and polyoma cells, secondary meningiomas, benign meningioma and malignant meningioma are all susceptible to meningeal sarcoma.
Prevention
Meningosarcoma prevention
1. Avoid harmful substances (promoting factors)
It is able to help us avoid or minimize exposure to harmful substances. Some related factors of tumorigenesis are prevented before onset. Many cancers are preventable before they are formed. Most malignant tumors are caused by environmental factors. Environmental factors and lifestyle refer to the air we breathe, the water we drink, the food we choose to make, the habits of activities, and social relationships.
2. Improve the body's immunity against tumors
Can help to strengthen and strengthen the body's immune system and cancer. The focus of our current cancer prevention efforts should first focus on and improve those factors that are closely related to our lives, such as smoking cessation, proper diet, regular exercise, and weight loss. Anyone who follows these simple and reasonable lifestyles can reduce their chances of developing cancer.
Promote the body's immunity against cancer: The most important thing to improve the function of the immune system is: diet, exercise and control troubles, healthy lifestyle choices can help us stay away from cancer. Maintaining a good emotional state and proper physical exercise can keep your body's immune system at its best, and it is also good for preventing tumors and preventing other diseases.
Complication
Meningeal sarcoma complications Complications intracranial hemorrhage cerebral edema
If surgery is performed, the following complications may occur:
1. Intracranial hemorrhage or hematoma: It is not related to intraoperative hemostasis. With the improvement of surgical techniques, this complication has been less frequent. The wound is carefully hemostasis and repeated flushing before closing the skull can reduce or avoid postoperative intracranial hemorrhage.
2. Cerebral edema and postoperative high intracranial pressure: decompressive drugs can be used to reduce intracranial pressure, glucocorticoids reduce brain edema, for patients with high malignancy, it is feasible to take decompression of bone flap.
3. Loss of nerve function: related to the important functional area and important structure of intraoperative injury, avoiding damage as much as possible during surgery, and symptomatic treatment after emergence.
Symptom
Meningosarcoma Symptoms Common symptoms Sensory disturbance Increased intracranial pressure Bone metastases
Meningioma is similar to benign meningioma, but the course is shorter. Because the tumor is located in the sagittal sinus or the cerebral surface, hemiplegia and partial sensation may occur. Epilepsy is also a common symptom of meningeal sarcoma, which is characterized by systemic seizures. Or localized episodes, patients with headache, vomiting and fundus edema and other symptoms of increased intracranial pressure, only from the clinical manifestations, difficult to distinguish from meningioma before surgery, in order to clarify the nature of the tumor, must rely on other auxiliary examination, literature It has been reported that meningeal sarcoma can undergo extracranial metastasis, mainly to the lungs and bones.
Meningeal sarcoma occurs mostly in the cerebral hemisphere. In addition to clinical manifestations, special examinations are helpful for diagnosis. Combined with X-ray film, cerebral angiography, CT and MRI, diagnosis can be made, but sometimes it is difficult to be complicated with benign meningioma. the difference.
Examine
Examination of meningeal sarcoma
1. X-ray and cerebral angiography
X-ray plain film can be seen on a wide range of needle-like radial bone hyperplasia and irregular skull destruction. The tumor can be eroded, destroying the skull to subcutaneous growth, the lesions are not neat around, the tumor can be subcutaneously grown through the damaged skull, and the cerebral angiography can be seen. The branches of the internal arteries supply blood to the tumor, and the local circulation of the tumor blood vessels is accelerated, and the diameter of the tube is not uniform.
2. CT scan
The unique "mushroom-like" tumor shadow can be seen. The surrounding edema is more serious than meningioma. The tumor can be deep into the brain parenchyma. The skull may be damaged and the tumor is necrotic. The above characteristics are rare in benign meningiomas, MRI. The T1 and T2 of meningiomas are high signals.
Diagnosis
Diagnosis and diagnosis of meningeal sarcoma
Should be differentiated from benign meningioma, generally difficult to distinguish before surgery, but meningeal sarcoma cerebral angiography showed that the internal carotid artery to the tumor blood supply is significant, a clear diagnosis requires postoperative pathology.
