dystrophic skin calcification
Introduction
Introduction to dystrophic skin calcification Calcinosiscutis is a disease caused by the deposition of insoluble calcium salts (mainly undetermined calcium phosphate or small amounts of calcium carbonate) in the skin or under the skin. It can be divided into three types: metastatic skin calcification, malnutrition calcification and idiopathic calcification. basic knowledge The proportion of illness: the incidence rate is about 0.004%-0.008% Susceptible people: no special people Mode of infection: non-infectious Complications: idiopathic skin calcification
Cause
The cause of dystrophic skin calcification
(1) Causes of the disease
A disease caused by deposition of insoluble calcium salts (mainly undesired calcium phosphate or small amounts of calcium carbonate) in the skin or under the skin.
(two) pathogenesis
Calcium deposits in previously damaged tissues, serum calcium and phosphorus levels are normal, and internal organs are not invaded.
The onset may cause calcium deposition by binding to calcium ions, such as alkaline phosphatase or free fatty acid, after tissue damage.
Prevention
Malnutrition skin calcification prevention
1. People living in the city, especially those in areas polluted by smoke, should consume more vitamin D.
2. Night workers, nuns, or people who cannot get enough sunshine because of their clothing and lifestyle should pay special attention to increasing the intake of vitamin D in their diet.
3. If you are taking anti-spasmodic drugs, you must increase your intake of vitamin D.
4. Children who do not have vitamin D milk must increase their vitamin D intake.
Complication
Malnutrition skin calcification complications Complications idiopathic skin calcification
Common complications: mass calcification, subepidermal calcification nodules.
Symptom
Malnutrition skin calcification symptoms Common symptoms Skin dull nail dystrophy Hard spot epidermis Calcium deposits Skin calcified beard Yellow
Generally can be divided into limited skin calcification and systemic calcification type 2.
1. Limited skin calcification has only a few calcium deposits, generally seen in patients with systemic scleroderma, occasionally in generalized scleroderma, when clinical systemic scleroderma develops calcium deposition, its clinical symptoms are like acral sclerosis, Acromegaly and calcium deposition are often associated with Thibierge-Weissenbach syndrome or CRST or CREST syndrome, the symptoms of which are usually caused by calcification of the skin, Raynaud's phenomenon, scleroderma, telangiectasia, and esophageal function. The obstacles constitute.
2. Systemic calcification is the majority of large calcium deposits, usually in patients with dermatomyositis. In addition to skin and subcutaneous tissue, muscles and tendons also have a large amount of calcium deposition.
Examine
Examination of dystrophic skin calcification
Histopathology: The deposition of granular calcium in the dermis is a large deposit in the subcutaneous tissue, and the calcium deposition site is mostly in the degeneration of collagen or adipose tissue caused by the primary disease before calcium deposition.
Diagnosis
Diagnosis and diagnosis of dystrophic skin calcification
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
