gastric neurofibromas
Introduction
Introduction to gastric neurofibroma Gastric neurofibromatosis is a neurogenic tumor, which is rare in clinical practice, accounting for 10% of benign gastric tumors and high malignant rate. Patients are more common in middle-aged people, and there is no significant difference between men and women. Most of the gastric neurofibromas are single, and can also be part of the systemic multiple neurofibromatosis. About 10% of gastric neurofibromas can undergo malignant transformation. It is more common in the small curved side of the distal end of the stomach. basic knowledge The proportion of sickness: 0.003%-0.005% Susceptible people: more common in middle-aged people Mode of infection: non-infectious Complications: anemia
Cause
Cause of gastric neurofibromatosis
(1) Causes of the disease
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(two) pathogenesis
Neurofibromas can occur in any part of the stomach, but are more common in the small curved side of the distal end of the stomach. The tumor is round, elliptical or nodular, with or without pedicles, and grows slowly, mostly in the subserosal to the stomach. Outward protrusion, a small number of submucosal growth protrudes into the gastric cavity, making the gastric mucosa gradually thinner, and even ulceration, gastric nerve fibers are mostly single, may also be part of the systemic multiple neurofibromatosis, about 10% of the gastric nerve Fibroids can be malignant.
Prevention
Gastric neurofibroma prevention
It is very important to maintain a good attitude, to maintain a good mood, to have an optimistic, open-minded spirit, and to be confident in the fight against disease. Don't be afraid, only in this way can you mobilize your subjective initiative and improve your body's immune function.
Complication
Gastric neurofibromatosis complications Complications anemia
Long-term chronic bleeding can cause severe anemia.
Symptom
Symptoms of gastric neurofibromas Common symptoms Black appetite loss indigestion
Gastric neurofibromatosis is characterized by hemorrhage, which is characterized by hematemesis or melena; another symptom is typical periodic ulcer-like pain. The application of drugs to treat pain can be temporarily relieved. Tumors near the pylorus or pedicled neurofibromatosis To the pylorus, there may be intermittent pyloric obstruction symptoms, large subserosal tumor compression of the stomach cavity can cause indigestion and loss of appetite, but there are also patients with gastric neurofibroma without any symptoms, larger gastric neurofibroma, on The abdomen may touch the mass and the medium hardness.
Examine
Examination of gastric neurofibromatosis
1. Patients with long-term chronic hemorrhage in blood routines have reduced red blood cells and hemoglobin, indicating iron deficiency anemia.
2. Fecal occult blood test can show positive results.
3. Histopathological examination is helpful for diagnosis.
4. X-ray examination showed that the stomach wall was a nodular bulge, or a semi-circular filling defect, and sometimes a shadow was seen in the filling defect area.
5. Gastroscopy shows the characteristics of submucosal tumors, some with pedicle or nodular.
Diagnosis
Diagnosis and differentiation of gastric neurofibromatosis
The cause of this disease has no specific symptoms, it is extremely difficult to diagnose before surgery. When there are the following signs, the diagnosis can be prompted: 1 benign tumor of the stomach with multiple skin neurofibromatosis, 2 long-term chronic blood loss (black stool), no other reason can explain 3, suddenly there is no cause of upper gastrointestinal bleeding, except for other diseases, 4X line suggests benign tumor of the stomach, after gastroscopy confirmed, biopsy can sometimes confirm the diagnosis.
It is difficult to distinguish with other benign tumors of the stomach. It depends on postoperative pathological examination. The identification of malignant tumors is mainly based on whether there is ulcer formation and mucosal destruction under X-ray, combined with gastroscopic observation and biopsy results. However, sometimes Differential diagnosis is still difficult. When there is major upper gastrointestinal bleeding, other more common diseases should be excluded first.
