Skin diseases caused by cobalt and its compounds
Introduction
Introduction to skin diseases caused by cobalt and its compounds Cobalt is a relatively rare element that can be used to make alloys. Cobalt and its compounds can be used as catalysts for chemical synthesis, as well as in the manufacture of paints, pigments, glass, glazes and electrode plates. Common cobalt compounds are cobalt oxide (CoO), high cobalt (Co2O3), cobalt sulfate (CoSO4) and cobalt chloride (CoCl2·6H2O). The trivalent cobalt salt is generally unstable and does not normally exist under the conditions. basic knowledge The proportion of illness: 0.005% Susceptible people: people who are prone to long-term contact with cobalt Mode of infection: non-infectious Complications: pruritus
Cause
Causes of skin diseases caused by cobalt and its compounds
(1) Causes of the disease
Exposure to cobalt compounds, cobalt dust and cobalt salts, causing allergic contact dermatitis and ecchymoses,
(two) pathogenesis
After exposure to cobalt compounds such as cobalt dust and cobalt salts, skin damage to allergic contact dermatitis and ecchymoses occurs.
Prevention
Prevention of skin diseases caused by cobalt and its compounds
Out of contact with cobalt dust and cobalt salts, the environment of cobalt and its compounds. Since the disease is clearly exposed to cobalt and its compounds, avoiding contact with such compounds is the most effective way to prevent this disease. Enhance personal protection, including wearing long rubber gloves and long boots. Use long aprons, wear protective glasses, masks, etc., to avoid contact with air contaminated by vanadium and its compounds. If contact is inadvertent, it should be cleaned immediately to avoid damage to the skin.
Complication
Complications of skin diseases caused by cobalt and its compounds Complications pruritus
Skin lesions often occur suddenly. In order to limit the number of red hulls of different sizes, the skin lesions mostly disappear for half an hour to several hours, and they are violently itchy and burning.
Symptom
Symptoms of skin diseases caused by cobalt and its compounds Common symptoms Freckles
1, contact with cobalt dust and cobalt salts can cause allergic contact dermatitis and ecchymosis, usually, allergic to cobalt and often allergic to nickel coexist.
2, contact with octacarbonylcobalt [Co2 (CO) 8] can cause a strong inflammatory response, severe cases can cause local necrosis.
3, exposure to cobalt dust and cobalt salt history, skin lesions consistent with allergic contact dermatitis and ecchymosis.
Examine
Examination of skin diseases caused by cobalt and its compounds
The disease usually has direct contact with elements and compounds containing cobalt. For contact dermatitis caused by other unknown contacts, the detection of cobalt should be made when it is suspected that cobalt damage causes the disease. For patients with severe contact dermatitis, due to the destruction of skin integrity, it may cause skin bacterial infection or fungal infection due to scratching, usually secondary to low constitution, long-term use of immunosuppressants and fungal infections such as nail fungus. Patients, such as concurrent bacterial infections, may have symptoms such as fever, swelling of the skin, ulceration, and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Diagnosis
Diagnosis and identification of skin diseases caused by cobalt and its compounds
The disease usually has a clear history of exposure to cobalt and its compounds, and clinical manifestations such as contact dermatitis appear, so there is usually no need to identify. The clinical manifestations of this disease are mainly urticaria, so it is clinically necessary to distinguish from urticaria caused by conventional allergic factors. The onset is more urgent, and the skin lesions often occur suddenly. In order to limit the number of red hulls of different sizes, the skin lesions mostly disappear for half an hour to several hours, and the sensation is intense and itching and burning. The position is uncertain, and it can be generalized or limited to a certain part.
