familial colon polyps
Introduction
Introduction to familial colon polyps Familial colonic polyposis belongs to adenomatous polyposis. It is an autosomal dominant hereditary disease. Occasionally, there is no family history. There are multiple adenomas in the whole colon and rectum. Most adenomas have pedicles and nipples. The shape is less common, the number of polyps varies from about 100 to thousands, ranging from the size of soybeans to several centimeters in diameter, often densely arranged, sometimes in strings, and its tissue structure is no different from general adenomas. basic knowledge The proportion of illness: 0.001% Susceptible people: good for infants and young children Mode of infection: non-infectious Complications: intussusception, intestinal obstruction, shock
Cause
Familial colon polyps
The disease is generally considered to be related to genetic factors, (APC gene mutation on the long arm of chromosome 5), often with a family history. Patients with extensive lesions can often occur in addition to the bleeding symptoms of general polyps, so surgery should be performed in time. Regular follow-up should also be used to prevent complications.
Prevention
Familial colon polyp prevention
Those with a positive family history should be alert to this disease, especially if there is mucus pus and blood, they should go to the hospital for treatment in time; if there are lips and surrounding skin, oral mucosa and special pigment spots or pigmentation of the fingers should be done in time for digestive tract angiography or fiber endoscopy and colon Mirror examination, found that multiple polyps are confined to the colon for feasible surgery, such as accompanied by full digestive polyps should be closely followed up; large bleeding, intussusception or intestinal polyps malignant lesions should be removed, Chinese medicine enema and other traditional Chinese medicine The method can be used as an adjuvant therapy.
Complication
Familial colon polyp complications Complications, intussusception, intestinal obstruction, shock
Intussusception, intestinal obstruction, major bleeding, hemorrhagic shock and other complications can occur, and can not be cured when accompanied by full digestive polyps.
Symptom
Familial colon polyp symptoms Common symptoms Abdominal pain Exhaust disorder Bloating colon Polyps Stop exhaust fatigue Constipation Pigment spots Defecation frequency Abnormal weight loss
1. The stool with mucus and bloody stools, increased stools, weight loss, fatigue, anemia and degree of abdominal discomfort or abdominal pain, or with extra-intestinal tumors such as chondroma, polyps are mainly located in the large intestine.
2. Anal examination can touch polyps, which can be accompanied by pigmentation or pigmentation and other tissue and organ tumors.
Examine
Examination of familial colon polyps
1. Colonoscopy, a large number of polyps are covered with colonic mucosa, and biopsy can confirm the diagnosis.
2. The sputum enema can be seen in multiple colons or extensive filling defects.
3. Anal finger examination can touch polyps.
Diagnosis
Diagnosis and diagnosis of familial colon polyps
diagnosis
It can be diagnosed based on medical history, clinical manifestations and laboratory tests.
Diagnostic identification
It should be differentiated from colorectal cancer, intussusception and other intestinal tumors.
