soft fibroma
Introduction
Introduction to soft fiber tumor Soft fibroma (softfibroma) is a disease of hyperkeratosis of the epidermis and proliferation of dermal connective tissue. This disease is also known as skin sputum. It is believed that soft fibroma can be used as a marker for rectal adenomatous colon polyps. Clinically, multiple filamentous or pedigree neoplasms are the main manifestations. basic knowledge The proportion of illness: 0.005% Susceptible people: usually women Mode of infection: non-infectious Complications: ischemic necrosis hypertriglyceridemia soft fibroma
Cause
Cause of soft fibroma
Genetic inheritance (90%):
The disease is also known as von Recklinghausen disease, autosomal dominant inheritance, neuroectodermal abnormalities caused by distorted dominant genes, commonly incomplete and simple type, clinically divided into single and multiple types.
Pathogenesis
The pathogenesis is still unclear. The tumor consists of loose connective tissue, similar to the connective tissue of the papillary layer. There are many capillaries, and there are three types according to histopathology.
1. Filamentous type: visible epidermal hyperkeratosis, acanthosis hypertrophy and papillary hyperplasia, a large number of dilated lymphatic vessels, in some cases (30%) visible sputum cells.
2. There is a pedicle type: the epidermis is thinned, the basal cells are flat and the pigment is deepened, sometimes the dermis is thin, and the center is mature fat cells.
3. Papular type: visible hyperkeratosis of the epidermis, regular acanthosis, occasional horn cyst.
Prevention
Soft fibroma prevention
The cause is not yet clear, so the prevention method is nothing less than: reduce infection as much as possible, avoid exposure to radiation and other harmful substances, especially drugs that have an inhibitory effect on immune function. First focus on and improve those factors that are closely related to our lives, such as quitting smoking, eating properly, exercising regularly, and losing weight. Appropriate exercise, enhance physical fitness and improve your disease resistance. Anyone who follows these simple and reasonable lifestyles can reduce their chances of getting sick.
Complication
Complication of soft fibroma Complications ischemic necrosis hypertriglyceridemia soft fibroma
Soft fibroma is a common sputum of the skin. It usually has few complications. Some of the bottom is small, and the upper part is larger. It may cause pedicle torsion, which may cause inflammatory infection, local pain, etc., and even lead to ischemic necrosis.
Some researchers have found that people with soft-fibroma often have hypertriglyceridemia, which may be the external appearance of hypertriglyceridemia. It is also found that patients with soft fibroma often have Intestinal polyps.
Symptom
Symptoms of soft fibroma Common symptoms Inflammatory papules Anal soft palate weight gain
Clinical manifestation
For small flesh-colored to dark brown needles large and large pedunculated and pedunculated papilloma, often occurs in the neck, often associated with small seborrheic keratosis, also common in the armpits, eyelids, followed by the trunk And the squirrels, some pedicled soft fibroids are teardrop-shaped, like a small pocket, even if the small pedicle is twisted and inflamed, tender, and even necrosis, the patient's weight gain or the number of gestation is often increased, Patients with colon polyps have a higher incidence of this disease. They have been reported as anal soft palate or skin wrinkles. They are now known as infantale perianal pyramidal protrusions. , usually for women, skin lesions occur in the front midline to the anus, and can be resolved over time, generally without treatment.
2. Classification performance
(1) Filamentous fibroids: multiple, common on the side of the neck, lesions are multiple filamentous protrusions, soft, about 2mm wide, about 5mm long.
(2) pedicled soft fibroma: more common in the neck, face or lower torso, the skin lesions are soft, the surface is smooth, about 1cm in diameter, usually with pedicles, if pedicle torsion and infarction, can cause pain and discomfort.
(3) papular fibroma: multiple small papules, 1 to 2 mm in diameter, with papules on the surface of the papules, which occur in the neck and underarms.
The skin type of the three types of skin lesions were normal or the pigmentation was slightly deeper.
Examine
Examination of soft fibroma
Skin lesions Histopathology: It is characterized by a hyperproliferative epidermis surrounding the connective tissue pedicle composed of loose connective tissue. The capsular papilloma usually has a flattened epidermis. The single-pocket type shows that the epidermis is thinned and flattened, and the basal layer pigment is increased; the multifilament-like type shows hyperkeratosis of the epidermis, papillary hyperplasia, and mild to moderate hypertrophy of the acanthosis. The dermis consists mainly of loose connective tissue, fibroblasts, collagen fibers, and dilated capillaries.
Diagnosis
Diagnosis and diagnosis of soft fiber tumor
diagnosis
Coffee stains are often the earliest manifestations, starting in infancy, and can be seen in 10% to 20% of normal people, but if more than 5, it suggests the possibility of this disease. According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
It needs to be differentiated from dermis, neurofibromatosis, multiple small seborrheic keratosis, hamartoma (connective tissue disease) and fibro-epithelioma.
