creeping perforated elastic degeneration
Introduction
Introduction to perforating elastic tissue degeneration Perforated perforated elastic tissue degeneration (elastosisperforansserpiginosa), Lutz reported that the disease is called perforating elastic fiber disease, it is also known as Lutz disease, and later has claudication follicular keratosis, known as follicular keratosis. The keratotic papules appear mainly on the neck and the back of the neck. The course of the disease is long and slow. After many years, there are self-resolving people. basic knowledge The proportion of illness: the incidence rate is about 0.0035% Susceptible people: no special people Mode of infection: non-infectious Complications: Mildew
Cause
Causes of perforated elastic tissue degeneration
Cause:
The cause is not clear.
Prevention
Perforation elastic tissue degeneration prevention
1, can eat more fresh fruits and vegetables to ensure the intake of vitamins.
2, avoid sweet and thick food: too sweet food such as candy, cream cake, Babao rice, glutinous rice cake group, lard and fat pork, sheep fat, egg yolk, these foods have the effect of moisturizing, will reduce the effect of treatment, Make the disease more difficult to treat.
3, avoid drinking: wine is warm and stimulating food, after drinking will increase damp heat, making the condition worse.
4, eat spicy fried and warm food: spicy, fried foods such as pepper, fennel, pepper, onion, mustard, roast chicken, fried pork chops, etc.; warm food such as beef, lamb, dog meat, etc. can help Get angry and aggravate your condition.
Complication
Perforated elastic tissue degeneration complications Complications
Pimples, abnormal teeth.
Symptom
Perforated elastic tissue degeneration symptoms common symptoms skin atrophy and hyperpigmentation dementia itching papule keratinization
A keratotic papule with a reddish or normal skin tone. The top is flat or conical. The diameter is about 2 to 5 mm. The horny plug can appear in the center. The rash is arranged in a ring or a semi-annular shape. There is a trend of limp development. The skin can be mildly atrophied, the skin color is light, and itching is light. The disease is common in young men. The rash is mostly on the neck side, and can also be applied to the face, limbs and trunk. After a slow, long-term illness, it can last for several years. The disease can be combined with tongue dementia, Ehlers-Danlos syndrome, elastic fiber pseudo-xanthoma, Marfan syndrome, Rothmund-Thompson syndrome, osteogenesis imperfecta, acral aging, congenital cataract, tooth dysplasia, etc. .
Examine
Examination of perforated elastic tissue degeneration
Histopathology: thickening of the epidermis, which has enlarged and irregular curved narrow ducts, through the dermis, the tube can be single or multi-cavity, through the outer mouth of the hair follicle duct, there may be degenerative basophilic substances and keratinized angle plugs The periluminum around the lumen and the lower mouth are chronic inflammation. The tissue cells and multinucleated giant cells form a foreign body granuloma. The eosinophilic elastic fibers penetrate into the lumen, and the elastic fibers of the dermal papilla layer are thicker than normal.
Diagnosis
Diagnosis and identification of perforated elastic tissue degeneration
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
1. Kyrle disease is penetrating hyperkeratosis. The rash is a widely distributed hyperkeratotic papule. The center is embedded with horny plug. The histopathological features are the phenomenon that the hair follicle has a horn plug, which is an autosomal recessive disease.
2. Reactive penetrating collagen disease is mostly related to trauma. It is common in children under 12 years old. Although the rash has a horn plug, the distribution of rash has no regularity. It usually disappears in 6-8 weeks. Histopathological features are epidermal necrosis. Collagen tissue degeneration, basophilic progressive necrosis, and into the annular epidermal lacuna, independent of hair follicles.
3. Puncture folliculitis is a common follicular papule of all ages. The hair follicle mouth is enlarged. There are curls and hair stems in the horny plug. The basophilic debris and elastic fibers can be seen in the perforation.
