Vulvar amebiasis
Introduction
Introduction to vulvar amebic disease Vulvar amebiasis is a disease caused by the invasion of the vulvar skin mucosa by the lytic tissue amoeba, which is secondary to intestinal amebiasis, which is directly infected by the amoebic trophozoite in the intestine, invades the vulva, and causes vaginal The vulvar mucosa is necrotic and forms an ulcer. basic knowledge The proportion of illness: 0.005% Susceptible people: women Mode of transmission: sexual communication Complications: cervicitis vulvar amoebiasis
Cause
Causes of vulvar amebiasis
Causes:
The amebic infection of the female genital is often directly infected through sexual intercourse. The amoeba cannot invade the intact skin. Only when the skin is scratched, cracked, cut, or surgical wound enters, the skin mucosa can be damaged. Diet, eat food or water contaminated with amoeba, form lesions in the colon, and produce amoebic dysentery, amoebic dysentery can spread directly from the bruised anus or vulva, but also through underwear, towels, The spread of daily necessities such as baths and infants is often secondary to severe amoebic dysentery.
Pathogenesis:
Amoeba is a Sarcodina yam. It is vegetatively propagated by means of pseudo-foot movements. It is also known as the amoeba, the only pathogenic amoeba in the human body. Two different forms, trophozoites and cysts, in a neutral or weakly alkaline environment, the cysts are converted into trophozoites, which form cysts and long-term when the local environment is unfavorable to the amoeba Survival, but generally does not lead to clinical diseases, cysts are strong against the outside world, is an important source of infection, and is the main form of transmission of diseases, trophozoites can cause tissue dissolution, causing tissue necrosis and causing lesions, Once the pathogen has invaded, the pathogen with proteolytic activity can cause extensive dissolving necrosis of the host tissue to form abscesses and ulcers.
Prevention
Vulvar amebiasis prevention
1. Proper and timely treatment of amoebic dysentery or liver abscess is an important prerequisite for the prevention of genital amoebiasis.
2. Pay attention to improving nutritional status and enhancing physical fitness.
3. Pay attention to your own food hygiene and environmental hygiene, and pay attention to the spread between sexual partners, especially for asymptomatic carriers, should be treated in a timely manner to prevent transmission to others.
Complication
Vulvar amebiasis complications Complications Cervicitis vulvar amoebiasis
Often combined with amoebic cervicitis, intestinal amebiasis.
Symptom
Symptoms of vulvar amoebia common symptoms pustular granuloma nodules skin necrosis
Vulvar amoeba ulcer
Firstly, it appears as a local hard pustule, local redness, and then ulceration, ulcers have strong tingling, multiple ulcers are round or irregular, the boundary is clear, some edges can be everted, and the inner edge is inwardly recessed. It forms a deep piercing shape, and the ulcer spreads rapidly to the surrounding and deep. The ulcer fuses into a large ulcer of several centimeters to a dozen centimeters and a large piece of necrosis. The ulcer surface is dark red granulation tissue, and the surface is covered with necrotic tissue and pus. There are stench, individual connective tissue hyperplasia, tumor-like protrusion, hard surface ulceration, weak patients, which is more destructive, and may have inguinal lymphadenitis.
2. Vulvar amoebic granuloma
On the basis of ulcers, the granulation tissue at the bottom of the ulcer forms hyperplastic granuloma, which is a rugged papillary nodule or cauliflower-like bulge. The texture is hard, the bleeding is easy to touch, the surface has pus and bloody secretions, and there is stench. The amoeba can be found in the secretions.
Examine
Examination of vulvar amebic disease
1. On the fresh smear, the amoeba is 20~40m, there is active pseudopod. When HE staining, large cell bodies are visible, and the cytoplasm contains fine pink particles, which are observed by endocytosis in the cytoplasm. Red blood cells can distinguish whether the amoeba is in the pathogenic trophozoite stage. When the intestinal amoebiasis is suspected, a stool test should be performed.
2. Serological examination of amebiasis is not clinically applied, because serum antibody response often occurs several weeks after the invasion of Ameba, and asymptomatic carrier antibody detection is often negative, and the detection method has indirect hemagglutination. , immunofluorescent antibodies and enzyme-linked immunosorbent assays, serum antibody titers will continue for several months to several years after recovery, so it can be used to assist in diagnosis and epidemiological screening.
Histopathological examination: examination of the scraping and tissue sections from the lesion site at the edge of the ulcer.
Diagnosis
Diagnosis and diagnosis of vulvar amebic disease
The amoeba can be diagnosed by finding the amoeba in the pus and necrotic tissue of the ulcer surface.
Epithelial amoebic lesions need to be differentiated from vulvar tumors or other infectious diseases: epithelial tumors including squamous cell carcinoma, squamous cell carcinoma and basal cell carcinoma; condyloma acuminata; verrucous skin tuberculosis, tuberculous abscess and syphilitic flat condyloma, soft Kneeling and so on.
