Rana faecalis
Introduction
Introduction to frog fecal disease Basidiobolomycosis is caused by the genus Bacterium sphaeroides, which is reported by Indonesia in 1956. basic knowledge The proportion of illness: 0.0006% Susceptible people: no special people Mode of infection: non-infectious Complications: pruritus
Cause
Cause of frog fecal disease
Pathogen infection (60%):
The frog fecal mold is caused by the bacterium of the genus Armen - zygomycetes - frog faecalis.
Insect bites (20%):
The invasion portal is unknown. Some cases are related to insect bites before the onset. It may be the arthropod as the medium of transmission. The infection is a gradually increasing subcutaneous nodule. The subcutaneous nodules are hard, the boundary is clear, the touch is movable, and the surface skin is atrophied. Hypopigmentation or pigmentation, no ulceration, occasionally adhesion to the underlying skin but not adhesion to the muscle fascia. The nodules can enlarge the entire shoulder, arm, upper torso, face, neck and entire leg and buttocks. Individual cases can involve the liver, intestines and other internal organs and muscles.
Prevention
Frog fecal mold prevention
Primary prevention
(1) Separate susceptible patients with filtered air or laminar air to prevent cross-infection in hospitals.
(2) Control of diabetes, lymphoma and leukemia patients, strict control of immunosuppressive agents, cytotoxic drugs, anticancer agents, etc., have a certain preventive effect.
(3) Strengthen food management and prevent fungal pollution.
2. Secondary prevention
Because the disease is very urgent and serious, early diagnosis is extremely important. Because mucormycosis is often difficult to detect in secretions, and it is difficult to identify, early diagnosis mainly depends on clinical evidence: that is, the disease is urgent, the condition is fierce, and the first part of the disease is the nasal brain. Following the chest, abdomen, pelvis, stomach and skin, pathogenic factors include acidosis of diabetes, leukemia and lymphoma of lung infection, malnutrition of intestinal infection, such as protein deficiency in children, combined with clinical manifestations, experiments Room (including fungal culture) and pathological examination (secretion, extracts, scraping, etc.) may achieve rapid diagnosis. Once diagnosed, amphotericin B should be used immediately, and 1.2 mg/kg should be administered every other day. Immediate control, surgical debridement in the nasal cavity, there are also advocated combination therapy, in addition to amphotericin B, plus 5-Fc, itraconazole or fluconazole.
3. Three levels of prevention
Timely use of amphotericin B can reduce the mortality rate of this disease from 80% to 90% to about 50%, control diabetes, nasal necrotic tissue for surgical debridement, can improve the prognosis of this disease.
Complication
Frog fecal mildew complications Complications pruritus
The disease is a fungal infection, and the disease may be accompanied by itching, and the skin integrity is destroyed. Therefore, the patient may be infected with skin bacterial infection or other fungal infections, usually secondary to low constitution, or long-term use of immunosuppressants and ash. Patients with fungal infections such as nails, such as concurrent bacterial infections, may have symptoms such as fever, swelling of the skin, ulceration, and purulent secretion. Severe cases can lead to sepsis, which should be brought to the attention of clinicians.
Symptom
Frog fecal mold symptoms Common symptoms Skin atrophy and pigmentation nodules Skin adhesions Leukocytosis Subcutaneous nodules
The infection is a gradually increasing subcutaneous nodule, and the invasion portal is unknown. Some cases are related to insect bites before the onset of the disease. It may be the arthropod as the medium of transmission. The subcutaneous nodules are hard, the boundary is clear, the touch is movable, and the surface skin is atrophied. Hypopigmentation or pigmentation, no ulceration, occasionally adhesion to the underlying skin but not adhesion to the muscle fascia. The nodules can enlarge the entire shoulder, arm, upper torso, face, neck and entire leg and buttocks. Individual cases may involve liver, intestines and other internal organs and muscles, local lymph nodes are not tired, no reports of blood and lymphatic dissemination have been found, patients may have fever, and white blood cell counts increase.
Examine
Examination of frog fecal mold
1. Direct microscopic examination: the same as the ear frog fecal mold.
2. Fungal culture: The microscopic structure of the genus Pseudomonas sinensis can have different structures at different stages, and it has sexual and asexual two kinds of reproductive spores. The asexual spores are ascospores. When the conditions are not suitable, thick-walled spores can be formed.
Histopathology: Histopathology is the same as that of the ear frog.
Diagnosis
Diagnosis and identification of frog fecal mold
1. According to clinical manifestations.
2. Direct microscopy
The same as the ear frog fecal mold.
3. Fungal culture
The microscopic structure of the genus Pseudomonas aeruginosa can have different structures at different stages, with sexual and asexual reproduction spores.
