Skin diseases caused by mercury and its compounds
Introduction
Introduction to skin diseases caused by mercury and its compounds Industrial applications: Mercury and its compounds have varying degrees of toxicity in addition to cinnabar, but they are widely used in industry, with at least 80 industries associated with mercury. Mercury is absorbed by the salivary glands and combined with sulfides in the oral cavity to form a stimulating mercury sulfide, often causing stomatitis. If a large amount of mercury vapor is inhaled, it can cause acute poisoning such as encephalopathy, necrotizing bone disease and hand and foot tremor. basic knowledge The proportion of sickness: 0.003%-0.005% Susceptible population: people who have long-term exposure to mercury Mode of infection: non-infectious Complications: stomatitis, mental disorders
Cause
Causes of skin diseases caused by mercury and its compounds
Cause:
Exposure to mercury vapor causes contact dermatitis. Organic mercury such as phenylmercury can also cause allergic contact dermatitis. Inhalation of large amounts of mercury vapor can cause encephalopathy, necrotizing bone disease and tremors of the hands and feet.
Prevention
Prevention of skin diseases caused by mercury and its compounds
Strengthen personal protection, wear work clothes, gloves, masks, work environment conditions, and install ventilation and exhaust equipment.
Complication
Complications of skin diseases caused by mercury and its compounds Complications stomatitis
If a large amount of mercury vapor is inhaled, it can cause acute poisoning such as encephalopathy, necrotizing bone disease and hand and foot tremor.
Symptom
Symptoms of skin diseases caused by mercury and its compounds Common symptoms Mental disorders Oral mucosal leukoplakia Oral ulcers Oral blood bubbles Oral pain Limb tremor Mercury toxic tremor
Mercury is absorbed by the salivary glands and combined with sulfides in the oral cavity to form a stimulating mercury sulfide, which often causes stomatitis. If a large amount of mercury vapor is inhaled, it can cause acute poisoning such as encephalopathy, necrotizing bone disease and hand and foot tremor; Chronic poisoning caused by contacts is mainly caused by neuropsychiatric disorders (prone to excitement and mercury tremor) and stomatitis.
Examine
Examination of skin diseases caused by mercury and its compounds
The measurement of urinary mercury and hematuria reflects the absorption of mercury in the body to a certain extent, but it is often not related to the clinical symptoms and severity of skin damage caused by mercury poisoning. The normal value of urinary mercury varies from region to region. The normal upper limit of domestic urinary mercury is not more than 0.25mol/L (0.05mg/L) or the atomic energy absorption method is not more than 0.1mol/L (0.02mg/L). ). The normal upper limit of blood mercury is 1.5 mol/L (0.03 mg/dl). Chronic mercury poisoning patients may have changes in EEG amplitude and rhythm electrical activity, peripheral nerve conduction velocity slows, blood a2 globulin and reduced glutathione increase, and blood lysosomal enzyme, erythrocyte cholinesterase And serum sulfhydryl groups are reduced.
Diagnosis
Diagnosis and diagnosis of skin diseases caused by mercury and its compounds
The disease is mainly caused by mercury compounds such as oral mercury. Patients with acute corrosive stomatitis and gastroenteritis occur several minutes to tens of minutes after taking the drug. The patient complained of burning in the mouth and throat, and had nausea, vomiting, abdominal pain, followed by diarrhea. Vomiting and feces often have bloody mucus and shed necrotic tissue. Patients can often be accompanied by peripheral circulatory failure and gastrointestinal perforation. Acute renal failure can occur after 3 to 4 days (seriously within 24 hours). There may be liver damage at the same time. Inhalation of high concentrations of mercury vapor can cause fever, chemical tracheobronchitis and pneumonia, respiratory failure, and acute renal failure. Skin contact with mercury and its compounds can cause contact dermatitis and is allergic. The rash is a erythematous papule that can be fused into a piece or form a blister, and the pigmentation is followed. Generally, the cause of this disease is very clear, so the diagnosis can be determined according to the history of exposure and clinical manifestations, without identification.
