blue mole
Introduction
Introduction to Lancome Blue nevus (bluenevus), also known as benign mesenchymal melanoma (benignmesenchymalmelanoma), blue neural crest (blueneuronevus), chromophoroma (chromatophoroma), melanoma (melanofibroma), benign mesenchymal melanoma or Jadassohn-Tieche blue Etc., is a benign tumor composed of blue sputum cells. There are three types of blue dragonfly: common blue dragonfly, cell blue dragonfly and combined blue dragonfly. Ordinary blue sputum lesions are large, often progressing, and occasionally benign metastasis of lymph nodes. It can be born or it can be born after birth. In addition to common in the skin, it can also occur in the oral mucosa, cervix, vagina, spermatic cord, prostate and lymph nodes. basic knowledge The proportion of sickness: 0.002%-0.003% Susceptible people: no special people Mode of infection: non-infectious Complications: cutaneous mucinous tumor
Cause
Blue sputum cause
Melanocyte aggregation (30%):
Blue sputum is caused by the accumulation of abnormal melanocytes in the dermis, which is rare, often accompanied by pigmented nevus, cardiac myxoma, and mucocutaneous mucosa (LAMB syndrome). And associated with nodular mast cell proliferation, histology and pigment cells, mast cells have a certain relationship.
Abnormal neural crest (35%):
Through ultrastructural and acetylcholinesterase activity analysis, it is speculated that blue sputum may originate from Schwann cells or endogenous nerves. However, blue sputum cells can synthesize melanin and suggest the source of melanocytes. Blue mites are considered to be normal melanocytes. In the abnormal part, it has an abnormal function, and it is speculated that the common blue scorpion and the cell sputum are both benign proliferation from the abnormal pigment cells of the neural crest.
Prevention
Blue dragonfly prevention
Blue sputum is caused by the accumulation of abnormal melanocytes in the dermis, but the specific cause of the disease is not clear, and may have certain correlation with environmental factors, genetic factors, dietary factors, and mood and nutrition during pregnancy. Therefore, it is impossible to directly prevent the disease against the cause. Early detection, early diagnosis, and early treatment are important for indirect prevention of this disease. It can also reduce complications such as malignant sputum such as Ota, and antibiotics should be used as soon as possible for patients who have already developed infection.
Complication
Blue sputum complications Complications, skin myxoma
Often complicated by nodular mast cell hyperplasia, mucocutaneous mucosa of the skin.
Symptom
Blue sputum symptoms common symptoms papular nodular plaque
1. Common blue nevus (common blue nevus) Women are more common, usually acquired, from childhood, occur in the face and extremities, especially in the back of the hand and waist and hip, the skin lesions are mostly single, even Or several, often no more than 1cm in diameter, grayish blue or blue-black nodules, top round, solid texture, can be fused into a piece, clear boundaries, blue, blue-gray or blue-black pimples, can occur in Any part, but half of it occurs in the back of the hand and the back of the foot. This type of blue dragonfly is generally not malignant.
2. Cellular blue nevus is rare, common in women, usually present at birth, showing blue-gray or blue-black nodules or plaques, 1 to 3 cm in diameter, even or larger, usually with a smooth surface. Or irregular, clear boundaries, about half of the cases occur in the buttocks or lower back, the larger area, often accompanied by multiple satellite foci, this type of blue can be developed from congenital sputum cell sputum, more susceptible to malignant Melanoma.
3. Combined blue nevus (combined blue nevus) is a blue sputum with sputum cell sputum, generally darker in color, different in size, smooth or irregular surface, this type of blue mites may be malignant.
Examine
Blue dragonfly inspection
In addition to atypical melanocytes, common necrotic foci, and see residual melanocytes, can self-resolve or lighten in a few years, occurring in one shoulder and neck, upper supraclavicular region and upper arm, etc., posterior supraclavicular nerve and A pigmented lesion in the lateral cutaneous nerve distribution area of the arm. Histopathological examinations are helpful for disease diagnosis and classification diagnosis.
Diagnosis
Blue sputum diagnosis
According to clinical features, the diagnosis of blue sputum is not difficult, but the diagnosis requires pathological examination.
1. Skin fibroids: no melanocytes, dopa reaction positive.
2. Mongolian plaque: It is born at the time of birth and can be self-resolved or lightened in a few years.
3. Ota : The lesion is generally limited to the first unilateral trigeminal nerve, the second branch area, the central color of the patch is dark, and the edge is light.
