Fox-Fortis disease
Introduction
Introduction to Fox-Ottawa's disease Fox-fordycedisease (Fox-fordycedisease) is also known as axillary glandular sweat glands (aggressive gland) inflammation, sweat gland keratosis. It is a chronic, pruritic papular disease, which is more common in women and is more common in the apocrine sweat gland localization area. basic knowledge The proportion of illness: 0.005% Susceptible people: more common in women Mode of infection: non-infectious Complications: genital skin seborrheic dermatitis syringoma vulvar vaginal canal
Cause
The cause of Fox-Ottawa disease
Causes:
The cause is unknown, which may be an endocrine disorder, which leads to the formation and occlusion of the apocrine gland. The epithelial duct of the apocrine gland expands and ruptures, sweat is spilled into the epidermis, and emotional factors can promote seizures.
Pathogenesis:
May be under the influence of endocrine, dysfunction of apocrine sweat gland, and then cause aseptic inflammation of the apocrine sweat gland and cause the disease, sponge edema blister may appear in the wall of the hair follicle, that is, apocrine sweat gland retention blisters, hair follicle funnel The acanthosis is thick and there may be inflammatory cell infiltration in the dermis around the funnel.
Prevention
Fox-Ottaka disease prevention
prevention:
According to the cause of the prevention. Keep the vulva clean, educate the children to understand the importance of the vulva clean, avoid wearing nylon underwear, early treatment can be used in 1:5000 potassium permanganate warm bath, 2 ~ 3 times / d, the vulva keeps dry after cleaning.
Complication
Fox-Ottawa disease complications Complications vulvar skin seborrheic dermatitis sweat duct tumor vulvar sweat duct tumor
Damage may be confused with sputum, but it is more prolonged and a preliminary diagnosis can be made based on their location and clinical course. Clinically, lesions have typical tenderness, with reddish purple nodules, like sputum but appearing in the area of the apical gland, including (in order) the armpits, groin, around the nipple, and around the anus. In patients with a history of several years, it is characterized by pain, waviness, pus and sinus formation.
Symptom
Fox-Ottaka's disease symptoms Common symptoms Itching itchy pimples
Did not report pre-puberty or post-menopausal disease, after menopause, due to decreased gonadal activity and self-healing, damage only occurs in the dermatitis sweat gland skin, mainly axillary, followed by areola, umbilical fossa, pubic bone and The genitals are symmetrically distributed, and the basic damage is from the needle to mung bean-sized hair follicle papules. It is solid, smooth and round, fleshy or pale yellow, and does not fuse with each other. Some of the center of the papule is the hair follicle. When squeezed with fingers, it can be A small amount of slightly turbid liquid is squeezed out from the mouth of the hair follicle, the hair of the affected part is sparse or missing, and it is consciously itchy. Some patients have itching during menstruation. During pregnancy, due to changes in gonadal secretion, the secretion of apocrine sweat glands is reduced, and the symptoms can be temporarily relieved. Even faded.
Examine
Fox-Ottaka's disease check
The secretions were examined microbiologically. Histopathology: hyperkeratosis, hair follicle filling angle plug, hypertrophic spinous cell layer in the follicle funnel, vaginal atrophic vesicles in the dermis, degenerative changes in endothelial cells, lymphocytic infiltration around blood vessels and sweat glands.
Diagnosis
Diagnosis of Fox-Ottawa disease
According to the symptoms, after the female puberty, the menstrual period is aggravated, and the typical sweaty conical solid papules appear in the apocrine gland distribution area, which is the same as the normal skin color and the histopathological examination of the biopsy specimen can confirm the diagnosis.
Should be differentiated from local neurodermatitis, lichen planus, sweat duct tumors.
