Pseudomonas aeruginosa infection
Introduction
Introduction to Pseudomonas aeruginosa infection Pseudomonas aeruginosa (Pseudomonas aeruginosa), a pathogen of Pseudomonas aeruginosa infection, does not cause disease in normal healthy people, but is weak in the body, low in body resistance, or suffering from other serious diseases. It can be secondary to infection, and can even cause sepsis and life-threatening. basic knowledge The proportion of sickness: 0.01% Susceptible population: iatrogenic infection Mode of infection: contagious Complications: paronychia abscess ischemic necrosis
Cause
Causes of Pseudomonas aeruginosa infection
(1) Causes of the disease
Pseudomonas aeruginosa is a Gram-negative aerobic bacterium, which is found in soil, dust, water and a few human intestinal tracts. It can also temporarily parasitize the skin, mainly in the anus, genital area, armpits and external auditory canal.
(two) pathogenesis
Under normal circumstances, it generally does not cause disease. When the body's resistance is low, it can cause disease and can cause death. Typical strains produce blue-green pyocyanin and yellow-green fluorescein, which can also produce many kinds of enzymes. It includes hemolysin, an enzyme that inhibits the reticuloendothelial system, and a keratinolytic protease. The growth of Pseudomonas aeruginosa is often accompanied by the smell of grapes (specific rat smell), which is unique to trimethylamine.
Prevention
Pseudomonas aeruginosa infection prevention
Usually avoid trauma, maintain local cleansing, remove necrotic tissue, and use antibiotic ointment.
Complication
Pseudomonas aeruginosa infection complications Complications Paronychia abscess ischemic necrosis
Green nail syndrome, such as patients with water, can occur paronychia, ear chondritis infection caused by Pseudomonas aeruginosa, can form an abscess when aggravated, due to empyema compression, can lead to ischemic necrosis of cartilage, the formation of ear deformities.
Symptom
Pseudomonas aeruginosa infection symptoms common symptoms fatigue, itching, crusting, gastrointestinal symptoms, low fever, abdominal distension, pustule abscess, muscle pain illusion
Skin infections can be of the following types:
1. gangrenous deep pustulosis, also known as ecthyma gangrenosum, common in leukemia, severe burns, decreased triads, advanced cancer or some serious consumptive diseases, clinical features of clusters of blisters, There is a purple-red blush around the circumference, and the blister content quickly becomes hemorrhagic. After the break, a round ulcer forms, and there is a black necrotizing suede in the center. The damage mainly occurs in the limbs, buttocks, which can cause Pseudomonas aeruginosa sepsis, cellulitis, and There are maculopapular rashes, plaques and crusting. Severe cases may be accompanied by hypothermia, thirst, bloating, hallucinations and syncope. Gram-positive bacilli can be detected in the vesicles, and Pseudomonas aeruginosa is cultured in blood.
2. Green nail syndrome The infection is limited to the fingertips. The clinical features are nail stripping. The nail stripping area is pale green. If the patient is exposed to water, paronychia can occur.
3. External otitis (Pternary otitis) Pseudomonas aeruginosa infection is confined to the external auditory canal, accounting for 70% of external auditory canal, manifested as external auditory canal purulence.
4. Inter-finger infection infection is limited to the fingers, between the toes, the performance refers to the impregnation between the toes, the infiltration is grayish white or green, and may be accompanied by tropical immersion foot syndrome.
5. Pseudomonas aeruginosa folliculitis (peudomonas aeruginosa folliculitis) Hair follicle papules, blisters, pustules on the skin, caused by water bath in the water contaminated by Pseudomonas aeruginosa, also known as bath folliculitis, consciously itching, With varying degrees of low fever, fatigue, headache, myalgia, lethargy and gastrointestinal symptoms, the course of the disease is about 7 days.
6. Pseudomonas aeruginosa balanitis (pseudomomas aeruginosa balanitis) caused by Pseudomonas aeruginosa parasitic in the glans, the glans develop deep erosion, exudation, conscious pain, usually no systemic symptoms.
7. Ear perichondritis (perichondritis) Ear skin trauma such as surgery, auricular acupuncture and other injuries caused by the perichondrial infection of Pseudomonas aeruginosa, severe pain at the beginning, accompanied by systemic fever, local redness, an abscess can form when aggravated, As a result of empyema compression, it can lead to ischemic necrosis of the cartilage, forming an ear deformity.
Examine
Examination of Pseudomonas aeruginosa infection
Histopathology: epidermal cells have liquefaction and degeneration, nuclear pyknosis, dermal telangiectasia and edema, and a large number of bacteria invade between collagen fiber bundles. Blisters are epidermis or subepidermal blister, and there are also bacteria in the blister, neutral granules. Cells and monocytes, subepidermal vesicles are sometimes hemorrhagic.
Diagnosis
Diagnosis and identification of Pseudomonas aeruginosa infection
According to the characteristics of clinical lesions and histopathology: epidermal cells have liquefaction and degeneration, nuclear pyknosis, dermal vasodilation and edema can be seen in the dermis, and a large number of bacteria invade between collagen fiber bundles can be diagnosed.
