halo mole
Introduction
Introduction to syncope Syncope (halonevus) refers to the appearance of depigmentation halo around the sputum cells, and the central pigmentation sputum subsides. Most occur before the age of 20, the incidence of syncope in patients with vitiligo is 18% to 26%, such as erythema or crusting, after a few months can self-resolve. However, there is also a central sputum that does not regress even if it shows signs of inflammation. Syncope can occur in the elderly or in children. It occurs in the trunk, especially on the back, and occasionally on the head and face. It is rare in the upper limbs. basic knowledge The proportion of illness: 0.02% Susceptible people: no specific population Mode of infection: non-infectious Complications: vitiligo
Cause
Cause of syncope
Hormones and cell function (40%):
The etiology of this disease is not completely clear. Hormones and cellular factors are related to the occurrence of diseases. In patients with syncope activity, there are lymphocytes and specific antibodies that can kill melanocytes. It is speculated that atypical pigment cells trigger immune cross-reaction and normal epidermal pigmentation. Cells and sputum cells are destroyed.
Pathogenesis: The pathogenesis is still unclear. It is speculated that atypical pigment cells trigger an immune cross-reaction, which causes normal epidermal pigment cells and sputum cells to be destroyed.
Prevention
Syncope prevention
Eat less sweets and snacks. The nutritional value of sweets and snacks is not high, and the polysaccharides have high heat energy. Long-term food can cause malnutrition, induce diseases, and affect children's normal development. Therefore, parents should limit or even prohibit sweets and snacks for children. Never let sweets or snacks become Children's "staple food." Studies have pointed out that long-term consumption of sweets, the body's immunity will decline, and it is easy to suffer from diseases such as colds.
Complication
Syncope complications Complications
Vitiligo associated with syncope is currently common in the clinic. The clinical manifestations of syncope and vitiligo are white pigmentation spots, and the changes in histopathology and ultrastructure are similar. It is often seen that when the central sputum disappears, the white halo expands, and other parts of the body follow. A new case of white spot is issued.
Symptom
Syncope symptoms common symptoms scarring erythema (border clear...
1. It is good for young people's back, often single or multiple, which lasts for several months or years. Most of them can be regressed, but they can recur.
2. Skin lesions are surrounded by a decolorized area or halo around the melanocytes. Occasionally, inflammation, such as erythema or scarring, can resolve by itself after a few months, but there is also a central sputum that does not show signs of inflammation. A case in which the pigment has subsided and the discoloration halo has recovered.
3. Some patients have circulating anti-malignant melanoma cell cytoplasmic antibodies, and this antibody disappears as the syncope subsides.
Examine
Syncope check
Histopathological examination:
Usually complex sputum, early dermal superficial layer or junction, a large number of sputum cell nests and dense inflammatory cells infiltration, inflammatory cells are mostly lymphoid cells, a few are pigment-containing macrophages, sputum cells are damaged by inflammatory cell infiltration, late The sputum cells gradually decreased, and finally the inflammatory cells disappeared. The melanocytes in the epidermis were reduced or disappeared in the early stage of decolorization. The melanin and dopa-positive melanocytes in the epidermis at the top of the sputum disappeared slowly, but eventually disappeared after the syncope subsided. Completely disappeared, syncope without infiltration of inflammatory cells will not subside.
Diagnosis
Syncope diagnosis
diagnosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
1. Early syncope and malignant melanoma identification Histopathological sputum cell nest is often limited to the superficial dermis, inflammatory cells are more obvious, and diffusely distributed throughout the lesion, not concentrated around the lesion like malignant melanoma.
2. Pigmented sputum Peripheral dermatitis refers to the temporary general inflammation of the periorbital week, which should be distinguished from syncope.
