papillary sweat gland adenoma
Introduction
Introduction to papillary small sweat gland adenoma The papillary adenoma (papillaryeccrineadenoma) was first reported in 1977 by Rollon and Helwig. basic knowledge The proportion of illness: 0.02% Susceptible people: no specific population Mode of infection: non-infectious Complications: endocrine disorders
Cause
The cause of papillary small sweat gland adenoma
(1) Causes of the disease
The causes of papillary small sweat gland adenomas are quite complex, including genetics, natural aging, female hormones, and personal physique.
1. Related to heredity: This disease is a tumor-like tumor, sometimes with a family history.
2. May be related to endocrine disorders.
(two) pathogenesis
Histochemical studies have demonstrated that syringoma contains phosphorylase and hydrolase of the origin of a typical small sweat gland. A number of cystic ducts and some solid epidermal cell cords are visible in the upper and middle portions of the dermis, embedded in the fibrous matrix. The wall of the saccular catheter is often lined with two layers of cells, mostly flat. The inner cell is occasionally vacuolated. Some of the outer wall cells of the catheter are convexly curved outwards, shaped like a comma or a scorpion. In serial sections, these cystic ducts were seen to be connected to the dilatation sac of the intraepithelial catheter, but not to the apocrine secretory segment below.
Prevention
Papillary small sweat gland adenoma prevention
1. Minimize infection and avoid exposure to radiation and other harmful substances, especially drugs that have an inhibitory effect on immune function.
2, appropriate exercise, enhance physical fitness, improve their disease resistance.
3, should first focus on and improve those factors closely related to our lives, such as smoking cessation, reasonable diet, regular exercise and weight loss. Anyone who follows these simple and reasonable lifestyles can reduce their chances of getting sick.
Complication
Papillary small sweat gland adenoma complications Complications, endocrine disorders
This disease is a chronic disease and will not subside on its own. Some papillary small sweat gland adenomas have no change in static for many years. When people have trauma, overwork, menstrual period or endocrine disorders and other human immunity, the rash can gradually increase or increase or merge into a large one. Nodular sweat adenomas make treatment more difficult and treatment time longer.
Symptom
Papillary small sweat gland adenoma symptoms common symptoms nodules
It is characterized by dermal nodules mainly located in the extremities, which occur in black people and are prone to recurrence.
Examine
Examination of papillary small sweat gland adenoma
Histopathology: A dermal tumor with clear boundaries and no envelope, consisting of two layers of branched tubules. Immunohistochemical analysis indicated differentiation into the secretion cells of the small sweat glands.
Diagnosis
Diagnosis and differentiation of papillary small sweat gland adenoma
diagnosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
1. Xanthoma: common in the upper iliac crest, yellow pimples or plaques, often symmetrically distributed. More common in middle-aged women, often accompanied by hyperlipoproteinemia.
2. Flat warts: mainly found in adolescents, mostly in the face, but the lower jaw is not a good hair part, in addition to the face, it can also be seen on the back of the hand, for the surface is smooth, hard, pink, light yellow, light brown or normal skin color of sesame Flat papules to the size of soy beans. Scattered or distributed in groups. Generally asymptomatic, occasionally painful. Can disappear by itself, histopathology can be diagnosed.
3. : skin lesions can occur in any part of the body, is pale yellow or brown-black scorpion-like papules, the surface is hyperkeratotic, rough, mostly linear distribution. Histopathological examination showed hyperkeratosis of the epidermis, papillary hyperplasia, hypertrophy of the acanthosis, and increased melanin in the basal layer, but no sputum cells.
4. Papillary sweat duct cystadenoma: more common in the scalp, lesions are single papillary nodules, plaques, surface exudation, scarring. Histopathological examination showed papillary hyperplasia of different degrees of epidermis, and irregularly formed into a papillary sac cavity.
