abdominal aortic thrombosis syndrome
Introduction
Introduction to abdominal aortic thrombosis syndrome Abdominal aortic thrombosis syndrome (LericheSyndrome), also known as aortic bifurcation occlusion syndrome, terminal aortic thrombosis syndrome, progressive aortic end partial thrombosis syndrome, terminal aortic atresia syndrome, Chronic abdominal aortic iliac artery occlusion, isolated abdominal aortic iliac artery disease. basic knowledge Sickness ratio: 0.0001% Susceptible people: no special people Mode of infection: non-infectious Complications: aneurysms
Cause
Causes of abdominal aortic thrombosis syndrome
Cause:
Abdominal aortic thrombosis may form a thrombus due to aneurysm, trauma, tumor or foreign body damage to the wall, and the aorta is slowly occluded, which may have the opportunity to establish a collateral circulation, generally causing poor blood supply to the lower extremity. A typical large embolization can result from a mixture of large atherosclerotic material, thrombus, and bile alcohol crystals that fall off into the arterial circulation. Small embolization is caused by the release of bile alcohol crystals or by the shedding of ulcerative arteriosclerotic spots.
Prevention
Prevention of abdominal aortic thrombosis syndrome
1, pay attention to keep warm, blood vessels, especially coronary arteries are prone to contraction and spasm in the cold winter, blood supply is insufficient, and may lead to embolism, we must pay great attention to keep warm.
2, the patient should not be morning exercise, because the human body's nervous system is in a state of inhibition during sleep, lack of vitality, sudden and substantial exercise in the morning, sudden increase in nerve excitability, easily induced arterial embolism, should pay attention to this problem in winter.
3, tonic should be moderate, China's folks have the habit of winter tonic, winter people's exercise is originally less, coupled with a large number of hot food and nourishing medicated wine, it is easy to cause increased blood lipids, induce arterial embolism, so winter tonic must be based on individual Physical fitness.
4, to maintain a balanced mentality, emotional excitement is a taboo for vascular disease, coronary heart disease, hyperlipidemia patients should especially relax their minds, do not let the mood ups and downs too much.
5, proper exercise, reduced exercise will also cause slow blood flow, elevated blood lipids, so it is necessary to rationally arrange exercise time and control the amount of exercise. In the winter, you should wait until the sun rises and then exercise. At this time, the temperature will rise, which will prevent the body from suddenly getting cold and irritating.
Complication
Complications of abdominal aortic thrombosis syndrome Complications
Complicated aneurysms, arterial trauma, tumors, etc.
Symptom
Symptoms of abdominal aortic thrombosis syndrome Common symptoms Fatigue and blood movement disorder Shock skin pale
1. Waist, thigh, calf fatigue, pain during exercise.
2. Can not touch the lower extremity artery pulsation.
3. The lower limbs are pale and cold.
4. Male patients have impotence and difficulty in penile erection.
Examine
Examination of abdominal aortic thrombosis syndrome
1. Endothelin-1 assay: Endothelin-1 (ET-1) is the only endosome synthesized and secreted by vascular endothelium. ET-1 has strong vasoconstrictive activity and stimulates endothelial cells to release t-PA. In the population distribution, the plasma level of ET-1 in the elderly is higher than that of the population, which may be one of the factors that are susceptible to thrombosis in the elderly.
2. Increased thrombin regulatory protein: thrombin regulatory protein, thrombomodulin, is a receptor for thrombin, a single-chain anticoagulant glycoprotein present on the surface of endothelial cells, and TM binds to thrombin on the surface of endothelial cells. Complex, which specifically converts protein C to activated protein C (APC), TM is one of the sensitive specific molecular markers that reflect endothelial cell damage, and plasma or endothelial cell surface TM increases, indicating hypercoagulable state And thrombosis.
3. Platelet examination: including platelet adhesion, increased aggregation; increased plasma platelet release, especially alpha-specific thrombin (-TG) and platelet factor 4 (PF4) in alpha particles and platelet alpha particles Membrane protein GMP-140 increased, plasma serotonin release of serotonin was increased and platelet concentration decreased; plasma TXA2 metabolite TXB2 increased and/or prostacyclin product (6-keto-PGF1) ) reduced; both respond to platelet activation.
Diagnosis
Diagnosis and differentiation of abdominal aortic thrombosis syndrome
Abdominal aortic thrombosis In addition to lower extremity symptoms, there are often some abdominal symptoms. If you do not check carefully, it is easy to misdiagnose. The following points are helpful for diagnosis:
1 patients with severe conditions, mostly accompanied by shock.
2 lower abdominal and arm pain and sensory disturbances.
3 can be accompanied by gastrointestinal symptoms, such as vomiting, loose stools, falling feeling.
4 from the beginning can be unilateral limb symptoms, followed by contralateral limb symptoms, and then signs of blood vessels and other cold blood vessels, and then the embolization can appear later.
Early identification of intermittent claudication caused by other causes.
