Mycobacterium kansasii infection
Introduction
Introduction to Mycobacterium kansii infection Mycobacterium kansasiiinfection was first discovered in Kansas City in the United States in 1953. It has been found throughout the world and the infection rate is on the rise. Water may be the habitat of the bacteria. basic knowledge The proportion of illness: 0.002% - 0.007% Susceptible people: no specific population Mode of infection: non-infectious Complications: subcutaneous fat granuloma
Cause
Causes of Mycobacterium kansii infection
(1) Causes of the disease
Mycobacterium kansasii is a slow-growing, Mycobacterium faecalis, 37 ° C is the optimal growth temperature, colonies can form in about 1 to 3 weeks, can not grow at 45 ° C, can form S on egg solid medium Shaped colonies, occasionally R-shaped, easy to emulsify, culture in the dark does not produce pigments, colonies can produce red crystal-like carrot pigment-like pigments after light irradiation, this is the characteristic of the bacteria, smear acid-resistant staining can be seen cross-bar Bacillus, containing one to several multi-stained granules, positive for nitrate reduction test and Tween hydrolysis test, negative for niacin test, peroxidase and neutral red test, sensitization in mice, intraperitoneal vaccination can cause Liver, spleen, lymph node self-limiting granuloma.
(two) pathogenesis
NTM has different potentials for human disease. In general, as a category, the human virus is not as strong as M. tuberculosis, and can be transferred to human body surface and secretions without causing disease and tissue invasion. It is generally caused by a cause, that is, in a host with local or systemic dysfunction, Kansas ramets invade the wounded skin wound, which can cause localized skin lesions, mainly causing lung infection.
Prevention
Kansas Mycobacterium infection prevention
Standardize the use of medical water, sterile liquids and liquid chemical disinfectants. When a liquid chemical disinfectant is required, it is necessary to ensure that the method of use, concentration, disinfection time, etc. comply with relevant regulations. At the same time, the concentration monitoring of the liquid chemical disinfectant in use is strengthened.
Medical institutions shall follow the aseptic technical operating procedures and regulate the use of medical water, sterile liquids and liquid chemical disinfectants to prevent secondary pollution. After the various infusion solutions or solvents are opened, the time should be indicated, the use should be standardized, and the patient should be avoided. Do not use the sterile liquid for more than 24 hours after opening.
Complication
Kansas mycobacterial infection complications Complications, subcutaneous fat granuloma
There is no complication of this disease.
Symptom
Symptoms of Mycobacterium kansii infection Common symptoms Nodular edema granuloma
Mainly invade the lungs, occasionally invade the skin and cause skin lesions. Skin lesions occur in areas that are susceptible to trauma, such as limbs, face, irregular nodules that are ridged, and some may be like sporotrichosis. Starts on the back of the hand and then extends to the forearm extension. The facial skin lesions can be damaged by pigmented scars. The superficial ulcers can be removed, and the lower extremity lesions can be gradually expanded into large areas of granulomatous plaques within a few years. The lower limbs may have mild edema, local lymph nodes are not swollen, and there is no systemic symptoms.
Examine
Kansas Mycobacterium infection check
Acid-fast bacilli can be found in abscesses and necrotic tissues.
Thickening of the epidermis, keratinization with parakeratosis, chronic granulomatous inflammation in the dermis, see mononuclear or multinucleated giant cells, may be associated with small abscesses or necrosis.
Diagnosis
Diagnosis and identification of Mycobacterium kansei infection
This disease is generally not confused with other diseases.
