menopausal keratosis
Introduction
Introduction to menopausal keratosis Menopausal keratosis (keratodermaclimactericum) is a localized keratoderma that occurs in menopausal women. It occurs only in women and is common in obese women between the ages of 35 and 60. basic knowledge The proportion of illness: 0.004% Susceptible people: obese women usually 35 to 60 years old Mode of infection: non-infectious Complications: Hypertension Neurodermatitis Thyroid dysfunction
Cause
Causes of climacteric keratitis
(1) Causes of the disease
The cause of this disease is unclear, may be related to genetic factors, environmental factors and autoimmune factors, may also be autosomal dominant keratinization abnormalities, and the specific cause has not yet been clarified.
(two) pathogenesis
The pathogenesis is still unclear. Histopathological examination showed that the epidermal hyperkeratosis was excessive and showed non-specific chronic dermatitis changes.
Prevention
Menopausal keratosis prevention
The etiology of this disease is not clear at present, and may be related to the dysfunction of secretions in menopause. Because of the loss of rhythm of hormone secretion, it can cause keratosis abnormalities, mainly manifested by progressive erythematous keratosis of bilateral palmar, and the boundary is obvious. Chronic. Therefore, this disease cannot be directly prevented. Early detection, early diagnosis, and early treatment are important for preventing this disease.
Complication
Menopausal keratosis complications Complications hypertensive neurodermatitis hypothyroidism
May be associated with high blood pressure, neurodermatitis, vaginal itching or hypothyroidism.
Symptom
Menopausal keratosis symptoms common symptoms dry skin papules grow slowly
The disease occurs only in women, and is common in obese women aged 35 to 60 years. It occurs in premenopausal or menopausal period. The palmar sac can be afflicted alone or at the same time. It is often located in the palm swell and heel, the sacral margin and other compression and friction parts. The skin lesions are scattered round or oval keratotic flat papules, which are slowly enlarged, thickened, and fused into a piece. In severe cases, the skin of the palmar is generally dry, and the skin of the knee joint is thickened and the winter is aggravated. Relief in summer, when the crack or secondary infection occurs, the activity is inconvenient due to pain, the course of the disease is chronic, and may be accompanied by hypertension, neurodermatitis, vaginal itching or hypothyroidism.
The keratotic damage that occurs in menopausal women in the palmar area can generally be diagnosed.
Examine
Examination of menopausal keratosis
Clinically, the disease is usually diagnosed according to the characteristics of the lesion and the pathological examination:
1. Characteristics of skin lesions: Symmetry occurs in the palm of the hand, local keratin is thickened, the color is flushed, it is scorpion-like, the surrounding boundary is clear, yellow-red, and the surface may have flaky scales. The rash can gradually develop to the back of the hands and feet, the extremities of the extremities, and the knee and elbow joints. Occasionally the thighs, upper arms, shoulders, neck and face can also be affected.
2. Histopathology: The layers of the epidermis were thickened, with the stratum corneum being the most prominent. The superficial dermis had telangiectasia and mild inflammatory cell infiltration.
3. Other examinations: For patients with possible infections, blood tests, C-reactive protein and secretion smears can be checked.
Diagnosis
Diagnostic diagnosis of climacteric climatology
However, it is necessary to exclude congenital and other acquired palmoplantar keratosis. The former has a family history and has an early onset. The latter is common in hair red pityriasis, chronic contact dermatitis, chronic eczema, fungal infection and manual labor.
