colorectal malignant lymphoma
Introduction
Introduction to large intestine malignant lymphoma Malignant lymphoma (Malignant Lymphoma) is a malignant tumor originating from lymphatic reticular tissue. The malignant lymphoma of the large intestine includes extranodal lymphoma originating in the intestine and malignant lymphoma in other parts of the gastrointestinal tract. Secondary lesions, the origin of the insidious onset, lack of specificity in the early stage, often due to delay in diagnosis and treatment and poor prognosis. Occurs in the end of the ileum and the cecum, which is rich in lymphoid tissue, followed by the right colon. The distribution characteristics can be limited, but it is generally more extensive than cancer. basic knowledge The proportion of sickness: 0.0045% Susceptible people: no specific population Mode of infection: non-infectious Complications: intussusception, intestinal obstruction, ascites
Cause
Causes of malignant lymphoma of the large intestine
The exact cause is unknown and may be related to radiation, chemical carcinogenesis and toxins.
Prevention
Prevention of colorectal malignant lymphoma
There is no effective preventive measure for this disease. Early detection and early treatment are the key to the prevention and treatment of this disease.
Complication
Complications of colorectal malignant lymphoma Complications, intussusception, intestinal obstruction, ascites
Late stage can be complicated by intussusception, intestinal obstruction and other organ involvement symptoms and signs, can also be associated with ascites and dyscrasia.
Symptom
Symptoms of malignant lymphoma of the large intestine Common symptoms constipation fecal column deformation thin ascites abdominal tenderness bloody abdominal pain stool habit change
1. Diffuse type: characterized by infiltration, diffuse thickening and hardening of the intestinal wall, showing that the intestinal segment loses normal luster, the intestinal lumen is narrow, and the peristalsis disappears. After injecting, the intestinal lumen cannot be expanded, and the mucosal surface can be thickened like a brain. The wrinkles of the shape can also be diffuse nodular changes, surface erosion or superficial ulcers, similar to invasive cancer, but involving a wide range.
2. Polyp type: The mass of the mass is broad, the surface is smooth or a nodular polypoid mass, which is easily misdiagnosed as benign polyp or polypoid carcinoma. The surface of the tumor may have ulcers and hemorrhage, and may cause intestinal stenosis. It can present multiple hemispherical polyps of almost equal size, similar to benign lymphoid polyposis, with a smooth surface and white color, but the local part is often thickened by infiltration, the colonic penumbra disappears, local stiffness, and peristalsis disappear.
3. Ulcer type: malignant lymphoma may present with malignant ulcer characteristics, but some patients may also show benign ulcer changes: the ulcer is flat and superficial, the surface is white moss, the circumference is flat, etc. In addition, there is an extraintestinal mass type. Induced by the growth of the intestine outside the intestine, the intestine can be compressed to make it narrow, but the mucosal surface is normal.
Examine
Examination of large intestine malignant lymphoma
Fibrocolonoscopy is the main method for diagnosing this disease. The positive rate of endoscopic is as high as 50% to 80%. It is worth noting that although it is sometimes suspected to be malignant under endoscopy, biopsy pathology can only detect inflammatory disease. Cell infiltration, no cancer, this is because the intestinal malignant lymphoma has certain characteristics such as histological and lymphocyte abnormalities, pathological mitotic figures, tissue structure damage, etc., but often due to shallow material, tissue The block is too small, the extrusion of the tissue clamps, etc. can not be diagnosed, so the biopsy of this disease is different from colon cancer, in addition to the mucosal material, it is necessary to grasp the submucosal tissue, and once the endoscopic results and pathological results When the time does not match, you should be alert to the possibility of this disease.
Diagnosis
Diagnosis and diagnosis of malignant lymphoma of the large intestine
Fiberoptic colonoscopy is the primary method of diagnosing this disease.
The disease should be differentiated from colorectal cancer. The clinical manifestations and medical history are similar. Sometimes fiberoptic colonoscopy can not completely distinguish the two. The diagnosis often depends on biopsy to identify.
