Multiple Gastrointestinal Polyposis Syndrome
Introduction
Introduction to multiple gastrointestinal polyp syndrome Generalized Gastrointestial Polyposis Syndrome refers to the occurrence of multiple polyps in the digestive tract (for young metaplastic or inflammatory polyps), abnormal ectoderm and severe intermittent diarrhea. A group of syndromes of gastrointestinal and neurological symptoms such as abdominal pain and numbness in the limbs. It was reported in 1955 by Crokhite and Canada, so it is also known as Cronkhite-Canada syndrome. The age of onset is mostly between 30 and 86 years old, and males are more than females, about 1.5:1. basic knowledge The proportion of the disease: the incidence of common diseases in this disease is around 9% Susceptible people: no specific people Mode of infection: non-infectious Complications: gastrointestinal bleeding, intussusception, cerebral thrombosis
Cause
Causes of multiple gastrointestinal polyp syndrome
The etiology is unknown, and no genetic factors have been found. Some people think that it may be related to the lack of delayed type immune response in the small intestine. The pathological gastrointestinal tract has obvious mucosal inflammatory reaction, which is most obvious in the stomach and small intestine. The duodenum is most common in the polyps. The end is also more, the diameter of polyps can vary from a few millimeters to 3 centimeters, the difference is large, most scholars believe that the polyps are young-type hamartoma-like polyps, gastric mucosal lesions similar to Menetriey.
Prevention
Multiple gastrointestinal polyp syndrome prevention
Pay attention to rest, work and rest, life in an orderly manner, and maintaining an optimistic, positive and upward attitude towards life can be of great help in preventing diseases.
Complication
Multiple gastrointestinal polyp syndrome complications Complications, gastrointestinal bleeding, intussusception, cerebral thrombosis
Common complications of this disease are gastrointestinal bleeding, infection, intussusception, cancer and thrombosis.
Symptom
Symptoms of multiple gastrointestinal polyp syndrome Common symptoms Diarrhea Abdominal discomfort Watery vitamin deficiency Nausea abdominal pain
Clinical manifestations of diarrhea is most prominent, may have abdominal discomfort and anorexia, nausea, vomiting, abdominal pain, diarrhea is a thin watery stool, 5 to 7 times a day, may have bloody stools or fat diarrhea and malabsorption syndrome, ectoderm Abnormalities usually appear several weeks to months before the symptoms of digestive tract. The performance refers to the color change of the nail. It can be brown, white, yellow or black. The surface of the nail is scaly, wrinkled or spoon-shaped, and can be atrophied and thinned. Splitting, loosening, shedding, skin pigmentation, brown spots, ranging from a few millimeters to 10 millimeters in diameter, neurological symptoms may have numbness in the limbs, some have a sense of taste, olfactory sensation or disappear, and some have epileptic seizures, Even fainting, and a considerable number of patients have malabsorption syndrome, protein-losing enteropathy, and therefore have malnutrition, hypoproteinemia, vitamin deficiency and edema anemia and other clinical symptoms, the common complications of this disease are gastrointestinal bleeding, Infection, intussusception, cancer and thrombosis.
Examine
Examination of multiple gastrointestinal polyp syndrome
1. X-ray tincture gastrointestinal angiography found multiple polyps images.
2. Digestive tract endoscopy revealed diffuse multiple polyps.
Diagnosis
Diagnosis and diagnosis of multiple gastrointestinal polyp syndrome
The main diagnostic criteria include:
1. Digestive tract symptoms and abnormal ectodermal manifestations of diarrhea and abdominal pain.
2. X-ray tincture gastrointestinal angiography found multiple polyps images.
3. Digestive tract endoscopy revealed diffuse multiple polyps.
The disease should be associated with hereditary gastrointestinal polyposis with mucocutaneous pigmentation (Peutz-Jegher syndrome), hereditary colon polyp syndrome (Canada syndrome), Turcot syndrome, Gardner syndrome and other gastrointestinal polyposis Identification, these diseases are not accompanied by abnormal changes in ectoderm, which is helpful for identification.
