blastomycosis
Introduction
Introduction to bud disease Blastomycosis, also known as bacillus bacillus or dermatitis, mainly invades organs such as lungs, skin and bones. It is caused by dermatitis (North America) buds, and most of them are thought to be saprophytic bacteria such as soil and wood. It can also infect animals such as horses and dogs. In areas with high incidence, it is necessary to do a good job of protection. Especially to prevent skin damage or masks. In case of damage, it is necessary to disinfect in time and handle the wound. Clean the animals such as horses and dogs. Improving the body's immunity is the key to reducing infection. Can be exercised and other means. At the beginning of buds, there are signs of respiratory infections, and the symptoms gradually disappear. After a few weeks, the symptoms are recurring, fever, joint and muscle pain and other symptoms of acute inflammation, and the symptoms gradually disappear, but a few patients develop inflammation of bones and joints. The lesion, the lesion is swollen, painful, red, but not as obvious as a purulent infection, after the redness and ulceration, resulting in a fistula that is not easy to heal. basic knowledge Sickness ratio: 0.0001% Susceptible people: no specific population Mode of infection: digestive tract spread Complications: acute respiratory distress syndrome
Cause
Cause of blastomy
Cause:
The disease is caused by dermatitis (North America) buds, but the bacteria have not been isolated in nature. Most of them are thought to be saprophytic bacteria such as soil and wood. They can also infect animals such as horses and dogs, which are biphasic bacteria. The tissue is yeast type, and the hyphal type is cultured at room temperature of 26-28 °C, and the two types can be converted by artificial.
Prevention
Bacterial disease prevention
In areas with high incidence, it is necessary to do a good job of protection. Especially to prevent skin damage or masks. In case of damage, it is necessary to disinfect in time and handle the wound. Clean the animals such as horses and dogs. Improving the body's immunity is the key to reducing infection. Can be exercised and other means.
Bacillosis is a disease caused by inhalation of dermatitis germination spores. In the laboratory, or into the frequently-occurring areas, it is necessary to do a good job of prevention. Improving immunity is the key to reducing infection.
Complication
Bacterial complication Complications, acute respiratory distress syndrome
1, lung bud disease can be complicated by pleural effusion, respiratory distress syndrome.
2, extrapulmonary germination is spread by blood flow, which can lead to the following infections of various tissues and organs: skin, prostate, epididymis, penis, kidney, spine bone, long bone end, subcutaneous tissue, brain, oral or mucosa, thyroid , lymph nodes, bone marrow and other tissues.
Symptom
Symptoms of geranosis common symptoms abscess granulomatous infectious fever periosteal reaction osteosclerosis
Clinical manifestation
At the beginning of buds, there are signs of respiratory infections, and the symptoms gradually disappear. After a few weeks, the symptoms are recurring, fever, joint and muscle pain and other symptoms of acute inflammation, and the symptoms gradually disappear, but a few patients develop inflammation of bones and joints. The lesion, the lesion is swollen, painful, red, but not as obvious as a purulent infection, after the redness and ulceration, resulting in a fistula that is not easy to heal.
The foot swollen disease mainly invades the foot, and the induration occurs first in the stab wound. After that, the pus is broken and the fat-like liquid is discharged, and the fish-like particles escape. The fistula is unhealed for a long time, and the tendon and bone are deep, and the foot suddenly It is swollen and loses its normal state, but the pain is often not significant. It does not affect the patient's walking in the early stage, and the course of the disease is slow and lingering, sometimes lasting for more than 20 years.
X-ray findings: good invasive long bone ends and bone processes, such as cancellous bones in the humerus nodules, tendons, iliac bones, etc., Cockshot believes that this is the result of the characteristics of these molds in the red bone marrow, the lesion is a single room Or multi-atrial osteolytic destruction, the boundary is clear, in most cases, the periosteal reaction is not obvious, there is very little dead bone formation, can also penetrate the joint, and more damage to the weight of the cartilage, spinal lesions with osteolytic destruction Lord, rarely accompanied by osteosclerosis.
Pathological description
For granulomatous lesions, trabecular bone necrosis, liquefaction, the production of abscesses and fistulas, microscopically seen granulomas and tuberculosis are very similar, but often found mold.
Examine
Examination of geranosis
Fungal culture can be diagnosed, but if there are characteristic thick-walled non-coated yeasts directly from sputum, pus or urine samples, wide-base buds with diameters >8~15m can be almost diagnosed, using Gomori Utopia Silver staining, Gridley or PAS staining for histopathological examination, can be distinguished from Cryptococcus neoformans, which is smaller than dermatitis buds, narrower base, coated, and can be stained with Mayer mucin card red or Masson-Fontana The melanin test detects that the dermatitis germination disease has a cross-positive reaction with the histoplasmosis antigen. The sensitivity of the test is not certain, and no other serological or skin tests can be used for the diagnosis of the disease.
Diagnosis
Diagnosis and identification of germination
Bacteria should be distinguished from other fungal diseases, tuberculosis and tumors. Skin lesions can be misdiagnosed as sporotrichosis, tuberculosis, iodine poisoning, basal cell tumors, and genital infections may be similar to tuberculosis.
Pulmonary dermatitis germination should be distinguished from other fungal diseases, tuberculosis and tumors.
