Campylobacter enteritis
Introduction
Introduction to Campylobacter enteritis Campylobacter enteritis is a gastrointestinal disease caused by Campylobacter infection. Campylobacter has endotoxin that can attack the small intestine and large intestine mucosa and cause acute enteritis. It can also cause outbreaks of diarrhea or collective food poisoning. The incubation period is generally 3 to 5 days, and the pathogenic sites for humans are the jejunum, ileum and colon. The main symptoms are diarrhea and abdominal pain, sometimes fever, occasional vomiting and dehydration. basic knowledge The proportion of illness: 0.002% Susceptible people: no special people Mode of infection: digestive tract infection Complications: sepsis, nausea and vomiting, abdominal pain, diarrhea
Cause
Cause of Campylobacter enteritis
Campylobacter jejuni can cause diarrhea in humans and animals. It is related to humans including Campylobacter jejuni, Campylobacter fetus and Campylobacter jejuni. It is the most common cause of Campylobacter jejuni. Campylobacter jejuni is slender, curved and spiral. Or comma-shaped, Gram-negative, growing well in a micro-oxygen environment at 42 °C.
After entering the intestine, the bacteria rapidly multiply in the environment containing trace oxygen, mainly invading the jejunum, ileum and colon, invading the intestinal mucosa, causing congestion and hemorrhagic injury. In recent years, some strains have been observed to produce cholera-like enterotoxin, causing intestinal lumen. The internal fluid secretion increases.
Prevention
Campycolitis prevention
The most important source of infection for jejunal flexion disease is animals. How to control animal infections and prevent animal excreta from polluting water. Food is vital. Therefore, three tubes are used to control water, tube dung, and tube food to prevent the spread of Campylobacter. Powerful measures.
At present, research on live attenuated vaccines and heat-killing bacteria are expected to play an important role in eliminating infection sources and preventing infection.
Complication
Curative enteritis complications Complications sepsis nausea and vomiting abdominal pain diarrhea
Can be complicated by sepsis, nausea, abdominal pain, diarrhea, dysentery, watery stool.
Symptom
Campylobacter enteritis symptoms common symptoms abdominal pain nausea sepsis diarrhea watery stool dysentery
Clinical manifestations: acute onset, fever, abdominal pain, diarrhea, nausea, vomiting, mild diarrhea, plastic watery stool, severe stool with sticky, blood, pus, such as bacterial dysentery, even bloody stool, stool daily 6 ~ 10 times, the amount is not much, severe cases up to 20 times, foreign reports that children with jejunal Campylobacter enteritis accounted for 60% to 90%, domestic reports accounted for 3% to 10%, may be due to different types of strains caused by disease, the course of disease May be complicated by mesenteric lymphadenitis, appendicitis, cholecystitis or sepsis.
Diagnosis of the disease: Rapid observation of the rapidly moving Campylobacter can be made under the dark field microscope or related microscope with fresh feces. The diagnosis depends on the feces for culture.
Examine
Examination of Campylobacter enteritis
Stool routine
Appearance is mucus or water, microscopic examination has more white blood cells, or more red blood cells.
The method of direct smear inspection is to apply a thin layer of feces on a slide and slowly heat it, then immerse the smear in 1% alkaline magenta for 10-20 minutes, then rinse thoroughly with water, mirror The smear showed fine, single or stringed, sea-European wing, S-shaped, C-shaped or spiral-shaped bacilli at both ends were positive.
2. Bacteriology examination
It is advisable to take the stool of the patient, the intestines, or the blood of the fever patient, the puncture fluid, etc., and use the selective medium to culture in an anaerobic environment to isolate the pathogen. If the colony morphology and special biochemical characteristics are typical, the diagnosis can be confirmed. .
3. Serological examination
Take the early and recovery period of the double serum for indirect coagulation test, the antibody titer is increased by 4 times or more, and the diagnosis can be confirmed.
Diagnosis
Diagnosis and identification of Campylobacter enteritis
(1) Bacterial dysentery, typical sputum, high fever, abdominal pain, diarrhea, diarrhea, bloody stool, abdominal pain in the lower abdomen or left lower abdomen, obvious pain in the left lower abdomen, and intestinal cord, accompanied by obvious urgency and heavy weight, fecal examination has more pus cells, phagocytic cells The heavy ones are often dehydrated, which is beneficial to the difference from this disease.
(2) Diarrhea caused by other bacteria, such as typhoid fever, pathogenic Escherichia coli, Yersinia, Aeromonas hydrophila, other anaerobic bacteria, etc., sometimes difficult to identify from clinical, relying on pathogens when suspected And serology to confirm the diagnosis.
(3) Intestinal infections must be differentiated from salmonellosis and brucellosis.
