ehrlichiosis

Introduction

Introduction to Erich Body Disease It is a febrile disease caused by ticks, Erich, and a ricketts-like pathogenic microorganism. Ehrlichia is an absolute intracellular parasite that forms small cytoplasmic inclusions in lymphocytes and neutrophils. People are bitten and sometimes infected with dogs carrying cockroaches. In the United States, most cases are found in the southeast and south-central regions. There are two types of Ehrlichia that are pathogenic to humans in the United States: E. chaffeenis causes human monocyte Ehrlichia disease and E, phagocytophilia and its related pathogens cause human granulocyte Ehrlich disease. E. canis is currently thought to cause human monocytic Ehrlich disease. basic knowledge The proportion of sickness: 0.00002% Susceptible population: men are more susceptible to infection than women Mode of transmission: insect vector transmission Complications: abdominal pain, diarrhea, coma

Cause

The cause of Ehrlich's disease

Ehrlichia is an absolute intracellular parasite that forms small cytoplasmic inclusions in lymphocytes and neutrophils. People are bitten and sometimes infected with dogs carrying cockroaches and are infected in the United States. Most cases are found in the southeast and south-central regions. There are two types of Ehrlichia that are pathogenic in humans in the United States: E. chaffeenis causes human monocyte Ehrlichia disease and E. phagocytophilia and its related pathogens cause human granulocyte Ehrlichia disease. E. canis It is currently believed to cause human monocytic Ehrlichia disease.

Prevention

Ehrlich body disease prevention

1. Being bitten by a worm can't kill the worm immediately. It should be blown away or the toxin is bigger. Go to the hospital in time.

2. Pay attention to personal protection when performing tasks in the affected area. Wear long-sleeved clothes, tie the belt, cuffs, trouser legs, and towel on the neck.

3. Take comprehensive measures, mainly to kill rats and kill cockroaches. Eliminate the cockroaches on the surface of livestock and in the barn. You can remove or spray insecticides such as trichlorfon and drip. The house should be ventilated and dry, fill the wall joints, block the caves, and clean the livestock sheds and poultry houses or spray the drugs to eliminate the breeding grounds and kill all kinds of wild rodents.

Complication

Ehrlich physical complications Complications, abdominal pain, diarrhea, coma

The patient develops maculopapular or ecchymosis, but E. canis rarely causes rash, abdominal pain, vomiting and diarrhea; diffuse intravascular coagulation, encephalopathy and coma can often occur.

Symptom

Ehrlich's body symptoms Common symptoms Aversion to cold, abdominal pain, diarrhea, chills, abnormal liver function, leukopenia, nausea

No matter what kind of infection, the symptoms and signs are the same. Although there are asymptomatic infections, most cases have sudden onset 12 days after being bitten, accompanied by fever, chills, headache and fatigue. Some patients develop maculopapular rash or sputum. Spotted rash, but E. canis rarely causes rash, abdominal pain, vomiting and diarrhea, hematological and hepatic abnormalities including leukopenia, thrombocytopenia and abnormal liver function, especially elevated transaminases, serological tests and PCR can help early diagnosis .

At present, Ehrlich's disease mainly occurs in the United States. Men are more susceptible to infection than women. Most people have had a history of bite 4 weeks before symptoms appear. The main clinical features are acute fever, headache, anorexia, myalgia, aversion to cold/cold war. , nausea/vomiting, weight loss, recently, E. The antigenicity between chaffesis and canine Ehrlich is very close.

Examine

Ehrlich physical examination

1. Hematology and liver abnormalities include leukopenia, thrombocytopenia, and abnormal liver function, especially elevated transaminases. Serological tests and PCR can help early diagnosis.

2. Isolation and identification of pathogens.

Diagnosis

Diagnosis and diagnosis of Ehrlich's body disease

diagnosis

Diagnosis can be based on the cause, symptoms and related tests.

Differential diagnosis

1. The rash of meningococcal septicemia is pink, rash, maculopapular rash or sputum in subacute; in the case of fulminant sputum fusion or ecchymosis, meningococcal rash develops rapidly in the acute phase, Spotted palpation feels soft; while Rickettsia rash often appears on the fourth day of fever and gradually becomes freckle within a few days.

2, in the rubella, the rash starts from the face, and then spread to the trunk and limbs and quickly merge; the rash of rubella is often scattered. Rubella is accompanied by swelling of the lymph nodes behind the ear, no signs of systemic poisoning.

3, mouse typhus, rash is non-purple, non-fusion state and not extensive; renal and vascular complications are not common, to conduct specific serological diagnosis, treatment should not wait until the differential diagnosis is completed.

4. Epidemic typhus typhus causes severe physiological and pathological abnormalities similar to Ehrlich's disease, including peripheral circulatory failure, shock, cyanosis, skin necrosis of the ecchymosis, gangrene of the acne, and hememia. Kidney failure, paralysis and coma. Epidemic typhus rashes first appear in the armpits and torso, then spread to the limbs, rarely in the palms, soles and face.

5, tsutsugamushi disease, rickettsia acne, accidental spot heat will have local eschar, popular history often helps identify.

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