Crude cottonseed oil poisoning

Introduction

Introduction to crude cottonseed oil poisoning Cottonseed, also known as kapok, cotton nucleus, is the seed of the mallow plant cotton grass. Cottonseed oil is a fatty oil extracted from cottonseed and is one of the edible oils of farmers in the cotton area. Cottonseed contains cottonseed pigment glands, mainly cottonseed phenolic pigments, which can cause damage to nerves, blood, liver, kidney and other organs. Mistaken cottonseed, cottonseed cake, large amount or long-term consumption of unrefined cottonseed oil (containing gossypol more than double the national standard) can cause gossypolpoisoning, patients are more common in cotton-producing areas. basic knowledge The proportion of illness: 0.005% - 0.008% Susceptible people: no specific population Mode of infection: non-infectious Complications: respiratory failure

Cause

Causes of crude cottonseed oil poisoning

The disease is caused by the consumption of crude cottonseed oil that has not been properly treated or the cotton cake after oil extraction. Gossypol is a toxic substance that can cause redness and hemorrhage, loss of appetite, nervous disorders, weight loss, and affect fertility. Consumption of cotton wool containing more gossypol can cause poisoning, and the patient's skin has a strong burning sensation accompanied by symptoms such as dizziness, wheezing, palpitation and weakness. Therefore, untreated cotton wool is not edible.

Prevention

Crude cottonseed oil poisoning prevention

Propaganda cottonseed is toxic, can not eat, crude cottonseed oil can be eaten after alkali treatment, cottonseed cake can be used as animal feed after three times of exposure or fermentation, free in commercial cottonseed oil and cottonseed cake Gossypol should be below 0.02% and should not exceed 0.05%.

Complication

Crude cottonseed oil poisoning complications Complications, respiratory failure

In severe cases, breathing and circulatory failure occur and die. The biological half-life of gossypol in the cottonseed oil is 48 hours. The heart, spleen, kidney, adrenal gland, pituitary, muscle and testicles have the highest radioactivity in the intestinal contents. The activities of the tissues are: stomach, intestine, Liver, heart, kidney, spleen, lung, blood, muscle, fat, testis and brain cause toxic abnormalities.

Symptom

Crude cottonseed oil poisoning symptoms Common symptoms Abdominal pain coma liver swelling, dizziness, nausea, high fever, lethargy, constipation, loss of appetite

Acute poisoning usually occurs 2 to 4 days after eating, loss of appetite, nausea, vomiting, dizziness, headache, bloating, constipation, abdominal pain, numbness of the limbs, lethargy, irritability, coma, convulsions, enlarged liver, jaundice, gastrointestinal Bleeding, as well as bradycardia, blood pressure, even breathing, circulatory failure and death, if you eat a lot of this product in the summer, some patients may have high fever, red skin, burning and itching.

Examine

Inspection of crude cottonseed oil poisoning

1, blood routine, urine routine.

2, blood potassium, blood sodium check. Can have nausea, vomiting, burning stomach, bloating, constipation.

3, the heavy spirits are wilting, irritability, hooliganism and even coma, may be accompanied by bradycardia, blood pressure, heart failure, pulmonary edema, liver and kidney failure.

4, high fever in summer, numb lips and limbs, red skin without sweat, burning, acupuncture or itching.

5, chronic poisoning may have dry skin, redness, more obvious after sun exposure, women have amenorrhea, male sperm reduction.

6, check: critically ill patients have hypokalemia and hyponatremia.

Diagnosis

Diagnosis and identification of crude cottonseed oil poisoning

Identification with other things poisoning. The toxicity of gossypol can be eliminated by wet heat treatment. In this process, the aldehyde group of the gossypol molecule condenses with the amino group of the protein to form "bonded gossypol", but the nutritional value of the protein is also greatly reduced in the process. The above deficiency can be compensated for by removing the gossypol by solvent extraction. Mainly have hypokalemia, muscle weakness, lethargy and loss of libido. Long-term application may produce irreversibility of testicular function. Patients with varicocele before taking gossypol are particularly prone to long-term or permanent damage to spermatogenic epithelium after taking gossypol, so those who need to restore spermatogenic function should Check the diagnosis in advance.

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