Eosinophilic non-allergic rhinitis
Introduction
Introduction to eosinophilic non-allergic rhinitis Eosinophilic nonallergic rhinitis (also known as non-allergic rhinitis with eosinophilia syndrome (NARES), a highly reactive nasal disease characterized by nasal secretions of eosinophilia . The cause of the disease is still unclear. Wayof (1991) speculated that it may be a pre-existing manifestation of aspirin intolerance syndrome. It has been confirmed that eosinophil degranulation can put two cytotoxic substances: the main basic protein ( MBP) and eosinophilic cationic protein (ECP), MBP and ECP can destroy mucosal epithelial cells and cause different degrees of epithelial damage. As a result, nerve endings are susceptible to stimulation, resulting in increased nasal reactivity, thereby presuming the clinical symptoms and susceptibility of NARES. Acid cell growth is closely related. basic knowledge The proportion of illness: 0.005%-0.007% Susceptible people: no special people Mode of infection: non-infectious Complications: sinusitis allergic rhinitis nasal tumor
Cause
Eosinophilic non-allergic rhinitis etiology
The cause of the disease is still unclear. Wayof (1991) speculated that it may be a pre-existing manifestation of aspirin intolerance syndrome. It has been confirmed that eosinophil degranulation can put two cytotoxic substances: the main basic protein ( MBP) and eosinophilic cationic protein (ECP), MBP and ECP can destroy mucosal epithelial cells and cause different degrees of epithelial damage. As a result, nerve endings are susceptible to stimulation, resulting in increased nasal reactivity, thereby presuming the clinical symptoms and susceptibility of NARES. Acid cell growth is closely related.
Prevention
Eosinophilic non-allergic rhinitis prevention
The disease is no effective preventive measures, early diagnosis and early treatment is the key to the prevention and treatment of this disease.
Complication
Eosinophilic non-allergic rhinitis complications Complications Sinusitis Allergic rhinitis Nasal tumors
There is no obvious complication of this disease, and there is no allergic reaction based on the increase of nasal secretions of eosinophils, showing symptoms of highly reactive nasal diseases.
Symptom
Eosinophilic non-allergic rhinitis symptoms Common symptoms Nasal hair loss Runny nose nasal discharge Nasal unilateral nasal obstruction Nasal itching
There is no allergic reaction based on the increase in nasal secretions of eosinophils, showing symptoms of highly reactive nasal disease, which can diagnose the disease.
Similar to vasomotor rhinitis and allergic rhinitis, it is often difficult for patients to explain the cause of the onset of symptoms. There was no characteristic change in nasal examination, but a large number of eosinophils were found in the nasal secretion smear, and the allergen skin test was negative.
Examine
Examination of eosinophilic non-allergic rhinitis
There was no characteristic change in nasal examination, but a large number of eosinophils were found in the nasal secretion smear, and the allergen skin test was negative.
Diagnosis
Diagnosis and identification of eosinophilic non-allergic rhinitis
diagnosis
There is no allergic reaction based on the increase in nasal secretions of eosinophils, showing symptoms of highly reactive nasal disease, which can diagnose the disease.
Differential diagnosis
It is differentiated from vasomotor rhinitis and allergic rhinitis.
