lacrimal gland hyposecretion
Introduction
Brief introduction of lacrimal gland secretion The lacrimal gland secretion is a kind of dry corneal and conjunctivitis caused by too little tear, which is divided into four types: primary, congenital, paralyzed and toxic. The disease should be treated promptly and reasonably, and the symptoms can only be alleviated, and the results are not satisfactory. The lacrimal gland itself is caused by diseases. Any disease that causes atrophy of the lacrimal gland can lead to a decrease in tear secretion, such as senile lacrimal gland atrophy, Sygly syndrome, and Migueliz syndrome. basic knowledge The proportion of illness: 0.07%-0.09% Susceptible people: no specific population Mode of infection: non-infectious Complications: keratitis
Cause
Lacrimal gland secretion dysfunction etiology
1. Primary: The disease caused by the lacrimal gland itself. Any disease with atrophy of the lacrimal gland can lead to a decrease in tear secretion, such as senile lacrimal gland atrophy, Sygly syndrome, and Migueliz syndrome.
2, congenital: congenital lacrimal gland absent.
3, paralytic: dominating the lacrimal gland facial nerve, trigeminal nerve, sympathetic nerve numbness, especially trauma, alcohol rock shallow nerve injection, can block tear reflex, stop tear secretion.
4, toxicity: diseases associated with toxemia such as high fever, typhoid, acute intestinal infectious diseases, and may be directly damaged by lacrimal gland secreting cells, such as atropine poisoning, food poisoning can cause decreased secretion of lacrimal gland.
Prevention
Lacrimal gland secretion dysfunction prevention
1. Partial eye massage and moist heat.
2, to avoid a bad working environment, to develop a habit of moderate blinking.
3. Preventive use of artificial tears in offices or in various adverse environmental conditions. However, the use of antibiotic eye drops must be used under the guidance of an ophthalmologist because the antibiotics and preservatives in the eye fluid have toxic effects on the normal ocular surface.
Complication
Lacrimal gland secretion dysfunction complications Complications keratitis
Epithelial shedding can occur in filamentous keratitis, and can also be accompanied by corneal infiltration.
Filamentous keratitis is a medical name for eye diseases. It refers to a condition in which the corneal epithelium is partially exfoliated and has a filament-like shape with one end attached to the surface of the cornea and the other end in a free state. Also known as filamentous keratopathy.
Symptom
Lacrimal gland secretion dysfunction symptoms Common symptoms Eye pain keratitis Corneal dry spots Tear film disappears Conjunctiva dry spots
1. Eye fatigue, foreign body sensation, dry eyes, and some burning, eye pain, red eyes, photophobia.
2. The symptoms are light and heavy, the early symptoms are foreign body sensation, and the disease develops with a burning sensation. Dryness of the eyes is the most obvious symptom, especially when used outdoors, when the wind blows, or when using computers, video games, etc. for a long time, it is more obvious when attention is reduced.
3. Getting up in the morning is difficult to blink, it seems to have a sticky feeling, the symptoms of dryness of the eyes are more significant, and more serious may be accompanied by increased eye secretions and eye fatigue.
4. The eyes are red and there are many debris on the eyelashes.
Examine
Examination of lacrimal gland secretion dysfunction
The following examination methods can be used for suspicious patients to confirm the diagnosis:
1. Tear secretion test (Schimer test): below 10 mm/5 min for low secretion.
2. Tear film rupture time (BUT): less than 10 seconds for tear film instability.
3. Corneal fluorescein staining: corneal epithelial defects can be observed and the height of the tear river can be judged.
4. Conjunctival tiger red staining: staining positive is dry inactivated epithelial cells.
5. Determination of tear osmotic pressure: If greater than 312mOms/L, the earliest diagnosis of lacrimal gland secretion is reduced.
6. Determination of tear lactoferrin content
Agarose immunization single diffusion method: tears lactoferrin value less than 69 years old patients less than 1.04mg / ml, patients over 70 years old than 0.85mg / ml, can diagnose lacrimal gland secretion dysfunction.
Diagnosis
Diagnosis and differentiation of lacrimal gland secretion
1. Symptoms include dry eyes and foreign body sensation.
2. Lack of glandular secretion and tear film instability.
3. Damage to the epithelial cells on the surface of the eye.
4. The osmotic pressure of the tears increases.
5. Increased viscous secretions in the eyes, dry up and down.
6. Sticky mucus sticks to the epithelium, which can cause pain when pulling the epithelial surface.
7. Epithelial shedding can cause filamentous keratitis, and can also be accompanied by corneal infiltration.
