Meibomian Adenocarcinoma
Introduction
Introduction to meibomian adenocarcinoma Meibomianglandcarcinoma is a malignant tumor originating from the sebaceous gland. It has a high incidence and is the second most common orbital malignant tumor. In terms of gender, women are more than men. In the diseased area, the lower jaw is more than the upper jaw, and its degree of malignancy varies greatly depending on the type. The low degree of malignancy lasts for many years, slowly increases, and the high degree of malignancy develops rapidly, causing early metastasis. Therefore, when there is a recurrent seizure-like lesion in the 40-year-old or older, it should be paid attention to. basic knowledge The proportion of illness: the incidence rate is about 0.001% - 0.003% Susceptible people: no special people Mode of infection: non-infectious complication:
Cause
Causes of meibomian adenocarcinoma
Due to obstruction of the eaves outlet, the secretions of the glands remain in the tarsal plate, causing chronic irritation to the surrounding tissues.
Prevention
Seesaw adenocarcinoma prevention
1. Tumor resection, wound healing, no recurrence.
2. Improvement: residual after tumor resection.
3. Unhealed: no change or deterioration.
Complication
Mesenteric adenocarcinoma complications Complication
It can expand into the iliac crest, pour into the lymphatics, and metastasize.
Symptom
Mesenteric cancer symptoms common symptoms subcutaneous nodules yellow nodules sputum
There are few symptoms in the early stage. The local manifestations are subcutaneous nodules, hard and non-adherent to the skin. It is quite like sputum granuloma. Some people mistakenly believe that the sputum sacral resection has recurrence. The lumps continue to enlarge and can be seen on the conjunctiva. See yellow nodules, the surface is not flat, and then form ulcers, there are cauliflower-like masses, easy to hemorrhage, and the degree of differentiation is lower. The lymphatic vessels can be transferred to the pre-auricular lymph nodes and submandibular lymph nodes earlier.
Examine
Examination of meibomian adenocarcinoma
No special inspection method can be observed with the naked eye.
Diagnosis
Diagnosis and diagnosis of meibomian adenocarcinoma
This cancer is clinically distinguished from the following three lesions:
Spasm
(1) Most of the sputum granuloma is far from the sacral margin, and the sacral sac is completely rare at the iliac crest. Conversely, the cancerous tissue is easy to spread along the meibomian gland duct, so the sputum margin is more common.
(2) Morphologically, the two are very similar in the early stage, but in cancerous tumors, the conjunctiva on the surface of the lesion tends to be rough, and sometimes yellow spots are seen. In the lesion of the sacral lesion, the conjunctiva is generally blue-gray or slightly congested. The surface is generally smooth.
(3) When the sputum is swollen, it can be seen to contain a glia-like content. If there is secondary infection and liquefaction, there will be gray-yellow liquid overflowing from the incision. In cancerous tumor, it is hard and brittle yellow-white. Tumor tissue, after the sacral granules are automatically worn out, can form polypoid granulation tissue, unlike the cauliflower-like masses that are rough as seen in cancerous tumors.
(4) During the youth, glandular function is exuberant, and it is prone to sputum granuloma. When people reach old age, the gland tends to shrink and the secretion function is reduced. Therefore, gingival granuloma is rare in the elderly. Therefore, when the elderly have recurrent seizures, it must be To warn of the possibility of plate adenocarcinoma, it is best to perform biopsy of the cut diseased tissue to determine the nature of the lesion so as not to be misdiagnosed.
2. Squamous cell carcinoma: Mesangial adenocarcinoma is very similar in pathology to squamous cell carcinoma, but there is a significant difference between the two in clinical practice.
(1) tarsal adenocarcinoma occurs in the upper jaw; squamous cell carcinoma occurs mostly in the lower jaw, and the meibomian adenocarcinoma is located deeper in the tarsal plate or deep under the eyelid skin, while squamous cell carcinoma originates from the epidermis of the skin. Generally shallower.
(2) Early meibomian adenocarcinoma is very similar to sputum granuloma. Early squamous cell carcinoma resembles sputum or papilloma on the skin surface, and advanced meibomian adenocarcinoma is older than squamous cell carcinoma.
(3) There are more female patients with meibomian adenocarcinoma than males, while patients with squamous cell carcinoma have more males than females and are older, but the age of meibomian adenocarcinoma is larger than that of squamous cell carcinoma.
(4) Both can metastasize, but the metastasis rate of squamous cell mesenteric carcinoma is 60% higher than that of squamous cell carcinoma (10%).
3. Basal cell carcinoma: The meibomian adenocarcinoma is easily misdiagnosed as basal cell carcinoma based on pathology alone, so it should be identified in combination with clinical manifestations.
(1) The lesions of the epiphyseal adenocarcinoma are deep. Between the skin and the conjunctiva, basal cell carcinoma generally originates from the epidermis of the skin, and the lesion is located shallowly. The lesion is located in the inferior iliac crest.
(2) Early meibomian adenocarcinoma resembles sputum granuloma, and the hard lumps of walnut-like lobes are formed under the skin in the late stage. After the rupture, there is yellow-white cancer tissue exposed, which resembles cauliflower-like, basal cell carcinoma is similar to sputum in the early stage, and hard sneak is formed in the late stage. Typical necrotic ulcers with curling.
(3) Women with meibomian adenocarcinoma have more women than men; in basal cell carcinoma, men and women are similar.
(4) The metastatic rate of basal cell type meibomian adenocarcinoma is about 40%, while basal cell carcinoma of the skin does not metastasize.
