Barrett syndrome
Introduction
Barrett Syndrome Barrett Syndrome refers to the replacement of the lower esophageal mucosa by the columnar epithelium of the stomach, also known as Barrett ulcer, chronic peptic ulcer and esophagitis syndrome. First described by Barrett in 1950, it is called Barrett syndrome. Intrinsic can be congenital, but often secondary to reflux esophagitis, esophagitis and ulceration on the basis of gastric-esophageal reflux. basic knowledge The proportion of illness: 0.002% Susceptible people: more common in middle-aged or elderly Mode of infection: non-infectious Complications: ulcer bleeding
Cause
Cause of Barrett's syndrome
The acid-resistant squamous epithelium is damaged, the acid-resistant columnar epithelium regenerates and gradually spreads up to the lower part of the esophagus. The ulcer can penetrate the esophageal wall, causing fibrosis of the mediastinum and lymphadenitis. If the blood vessel is damaged, it causes bleeding, mediastinum. The pleura may have purulent lesions, and the microscopic examination of the mucosa has abnormalities and hyperplasia of atypical columnar epithelium.
Prevention
Barrett Syndrome Prevention
Actively prevent reflux esophagitis.
Complication
Barrett's syndrome complications Complications ulcer disease bleeding
Can be complicated by perforation or bleeding.
Symptom
Barrett's syndrome symptoms Common symptoms Post-sternal pain nausea and vomiting heartburn ulcer perforation or bleeding dysphagia
The disease is more common in middle-aged or elderly people, mainly in cold food, hot food, especially after acidic food, or in the recumbent position, there is a recurrent episode of lower sternal pain and burning, the pain can be radiated to the neck. Shoulder or arms, late in the throat may have difficulty swallowing, vomiting, hematemesis, black feces, etc., in addition, may be complicated by perforation or bleeding.
Examine
Barrett's syndrome check
1. X-ray examination showed that the esophageal wall showed isolated crater-like ulcers or shadows. The distal folds of the crater disappeared or atypical wrinkles, and the lesions were stenotic and stenotic due to edema.
2. Esophagoscopy revealed crater-like ulcers, poor mucosal folds, inflammation and edema, hemorrhage, leukoplakia, and exfoliated cells without malignant cells.
Diagnosis
Diagnosis and identification of Barrett syndrome
It should be differentiated from other esophageal diseases such as hiatal hernia.
