multiple tic syndrome

Introduction

Introduction to multiple tic syndrome Multiple tic disorder, also known as tics-slang syndrome, is a syndrome or behavioral disorder characterized by exercise, speech, and convulsions in children. More common in children or adolescents, the duration of the disease is long, and can be relieved or aggravated. basic knowledge The proportion of illness: 0.001% Susceptible people: more common in children or adolescents Mode of infection: non-infectious Complications: ADHD in children

Cause

Multiple causes of tic syndrome

The etiology and pathology of this disease are still unclear. Some people speculate that it is an organic disease, mainly the dysfunction of the basal ganglia, which is the site with the highest dopamine content in the brain. One of the important physiological functions of dopamine is regulation. Exercise function, it has been reported that the rate of catecholamines (including dopamine) in the brain of patients with multiple tic disorder is accelerated. Some people think that this disease is closely related to mental factors. At present, there are also some cases based on clinical cure, which is considered to be lack of Protein, minerals, multivitamins and trace elements are closely related.

The protein and multivitamins, minerals, trace elements, lack of any nutrients or metabolic abnormalities that the human body needs may cause insufficient or excessive supply of certain substances, which may cause abnormal changes in human tissue structure or function. The specific performance is disease or brain disease.

A protein is a polymer compound with a certain conformation composed of amino acids. It is a substance associated with life activities, and the nuclear protein and its corresponding ribonucleic acid (DNA, RNA) are the main material basis of heredity, which causes hemoglobin to carry oxygen. And carbon dioxide and the body's immune function.

Children are still in a rapid growth stage. The development of large and small brains is at a critical stage. The metabolism is strong, the heat and nutrients required are higher than those of adults, and they enter puberty. At this time, the growth of height and weight is accelerated, the thinking ability is active, and the memory is the strongest. The most important period of long body and long knowledge in a lifetime, if the nutrient protein is insufficient, the synthesis and secretion of hypothalamic and pituitary hormones are limited, affecting maturity, often feeling lack of mental and physical strength, loss of appetite, fatigue, difficulty falling asleep, dreaming Easy to wake up, trouble, restless performance, etc.

From clinical observation, some cases are caused by physical stimuli (such as conjunctivitis, stiff neck, neck discomfort, nasopharyngeal inflammation) or stress induced (parental, excessive interference, separation anxiety, transfer, reprimanded, younger brothers born, started Caused by walking, etc., more is that these factors increase the incidence of tic disorder and aggravate the severity of the disease. In recent years, developmental pediatrics has placed special emphasis on the close relationship between the quality of mother-child relationship and the onset, such as excessive mother protection and high expectations. Excessive interference, neuroticism, blame and blame are particularly likely to induce or aggravate the tics of children. On the contrary, rational care, psychological support, and moderate blindness to tics can alleviate the condition.

Prevention

Multiple tic syndrome prevention

From the use of protein powder, deep sea squid oil capsules, natural B vitamin tablets, calcium magnesium tablets, wheat germ oil capsules and other methods of treatment, in the usual life, the diet should be balanced, appropriate supplements related nutrition The substance provides high-quality raw materials for hormone synthesis, ensures the secretion of hypothalamic and pituitary gonadotropins, promotes body maturation and development of the brain and cerebellum, and also supplements the essential amino acids, minerals and trace elements for the large and small brains, making the brain 5 Reduced serotonin synthesis, increased levels of tryptophan and serotonin reduce attention, induce sleep, produce hypnosis and stability, and promote large and small brain development and repair.

In recent years, it has been found that most patients with TS have a significant improvement in puberty twitching symptoms. Qian Lianhua et al.'s 9-12 year follow-up study of TS patients concluded that most of the TS outcomes may be better, but a small number of them are forced. Disease, conduct disorder and tics affect the patient's quality of life. Wang Jian's follow-up results of 65 patients with TS in 6 to 12 years showed: TS symptoms disappeared and the rate of improvement was 91%, and suggested the length of the TS patients, whether accompanied by Other mental illnesses, whether family history and previous history of neuropsychiatry may affect the prognosis of TS.

Complication

Multiple tic syndrome complications Complications, ADHD, obsessive-compulsive disorder

The most common comorbidities are:

(1) Attention deficit hyperactivity disorder (ADHD), which is mainly called pediatric hyperactivity disorder, is characterized by distraction and/or hyperactivity.

(2) Obsessive-compulsive disorder (OCD), including various obsessive-compulsive concepts and behaviors that occur alone or at the same time, continue to appear repeatedly in thoughts and actions, knowing that they are not right, cant stop, sometimes cant get rid of, sometimes its painful, and self-harm can occur. Such as biting the tongue, biting the finger, damaging the skin, disfiguring, etc., often leaving infections or scars, and even revealing suicidal thoughts that do not want to live, be very vigilant to prevent accidents.

(3) Conduct disorder (CD) and oppositional defiant disor2der (ODD), as the name implies, have anti-social tendencies and cannot be ignored. Many parents often mistakenly believe that these performances are not morbid, especially for ODD. Its just that the temper is screaming and suppressing, and the condition is worse.

(4) Learning Disability (LD) is impaired cognitive function, mainly dyslexia and mathematics difficulties, which can seriously affect academic performance.

(5) mood disorder (MD), if depression and mood are bad, adult-type alternating depression 2 mania can also occur in children and young people, and the relationship with TS is unknown.

(6) Anx2iety disorder (AD), mainly fear and uneasiness, such as fear of separation from relatives, fear of family members, fear of going to school, long-term fear of strangers, fear of social interaction, and even worry about the future. Uneasy and so on.

(7) Autism and related diseases, including language disorders and Asperger syndrome, which is the same as autism.

Symptom

Symptoms of multiple tic syndrome Common symptoms Abdominal wall involuntary axis movement Sleeping calf cramps Local limbs twitching lower extremity abduction cerebral vasospasm convulsions Limb convulsions

It is caused by children, mostly between 5 and 15 years old.

Clinical manifestations:

Commonly for the head, trunk, upper and lower limbs twitching, head twitching is nodding or shaking his head, stretching the neck, neck, blinking, shrugging, pouting, etc.; torso twist, abdominal wall involuntary axis; limbs twitching see pendulum Arms, raising hands, clenching fists, lower limbs abduction, lameness, etc.; speech twitching can be expressed as a strange cry in the throat, individual syllables, words or sentences are unclear, or say swearing words, the time of attack Less than a dozen times or even hundreds of times, the symptoms mostly disappeared during sleep, mental development is normal, no abnormalities in the nervous system examination, cranial CT prompts: "Cerebellar dysplasia", TCD prompts: "cerebral vasospasm and insufficient blood supply."

Auxiliary inspection:

EEG, IQ is normal, no positive signs in the nervous system examination.

Examine

Examination of multiple tics syndrome

EEG, IQ is normal, no positive signs in the nervous system examination.

Diagnosis

Diagnosis and identification of multiple tic syndrome

Differential diagnosis

First, the disease:

1 snoring physical disorder (transformation snoring), manifested as numbness, hypersensitivity, sudden blindness, sudden complete hearing loss; arrhythmia or laryngeal obstruction; limb paralysis, unable to stand or walk, but no muscle atrophy; , fell to the ground, convulsions, often flicking hands and feet, sometimes pulling hair, biting clothes.

2 snoring psychological disorder (separate snoring) manifested as a sudden emotional outburst, crying and laughing, hitting the head, pulling hair, biting clothes, smashing the chest, rolling around, often accompanied by dramatic changes in emotions and dramatic performance, and the heart Forgotten patients are characterized by selective forgetting of those related to psychological trauma or a certain stage of experience; patients with snoring suddenly leave the original activities and go out to roam for several days.

Because rickets are neurological diseases, sometimes they are irritating and there are no organic lesions. Therefore, many people think that rickets are evil diseases, ghosts and gods, and they are asking for help everywhere, not only being deceived. Money also often leads to aggravation of the condition and delays normal treatment.

Second, the dance disease :

According to the characteristics of the disease, including age, course of disease, dance-like involuntary movements, changes in muscle tone and muscle strength, and possible history and symptoms of rheumatic fever, diagnosis is relatively easy.

Third, epilepsy :

1, large episodes: about 50% of seizures, mostly between 1 year old or 14-17 years old, large episodes can be divided into four periods: (1) aura: dizziness, stomach discomfort, (2) During the period of tonicity: Sudden loss of consciousness, falling to the ground, head tilting back, limbs and rigidity, due to diaphragmatic spasm, the patient issued a "lamb" like screaming, face bluish, pupil dilated, apnea, lasting for tens of seconds, (3) Fringing period: the whole body muscles have rhythmic tics, often bite the tongue, foaming at the mouth, may be accompanied by incontinence, usually lasting 1-3 minutes, (4) recovery period: generally tens of minutes to wake up, patient Can not recall the process of the attack, body pain, fatigue, individual patients in the recovery period have madness, chaos and screaming, hitting people and destroying things.

2, small episodes: epileptic seizures, also known as absence of seizures, typical manifestations of patients with transient loss of consciousness, most of the consciousness is completely lost, occasionally the consciousness disorder is shallow, have some understanding of the surrounding, can hear questions, but can not answer The disturbance of consciousness is short-lived and frequent. Most of them are 2-15 seconds each time, no more than 1 minute, several times a day to dozens of times, sudden, sudden termination, manifested as sudden interruption of speech and activity, two eyes gaze Occasionally, it is turned upside down, sometimes pale, without aura, holding hands in the hands, sometimes breaking the rice bowl, after the attack stops, continue the original activities.

3, psychomotor seizures: on the background of disturbance of consciousness, often have illusions, hallucinations and automatic diseases, etc., due to more caused by temporal lobe lesions, it is also known as temporal lobe epilepsy, the age of onset is late in all types of epilepsy, more At the age of 20, the first onset, about 40% of patients have aura on the onset, feeling stomach discomfort, auditory hallucinations, odor, dizziness, nausea, fear, etc., clinical manifestations can be divided into: (1) only consciousness disorder: should Different from the seizure, the disturbance of consciousness at the time of attack is more than 1 minute, and the seizure is more than 1 minute. (2) The identification symptom: memory disorder is the most common, and some patients are familiar with strangers or strangers. Feeling, called "like deja vu", some people who are familiar with the environment or the environment, inexplicably create strange feelings, (3) emotional disorders: can produce episodes of emotional abnormalities, like sudden feelings of sadness, anger, fear, disaster, The end of the day, etc., (4) mental symptoms: such as illusion, when the hearing is abnormal, others talk to themselves like a wall, the illusion of seeing something like a layer of yarn, seeing the ground undulating Seeing that the object is distorted, the object becomes larger, and the object becomes smaller. (5) Psychomotor symptoms: common in automatic diseases, involuntary movements of the oropharynx, such as sucking, chewing, swallowing, etc. Wiping clothes, hand-lifting in the air, etc., sometimes more complex automatic symptoms are manifested in sleepwalking and soaring, etc., (6) complex type, manifested as a combination of complex symptoms. Some sudden bursts of impulses, and even illegal activities, such as wounding, destruction, self-injury, suicide, killing and so on.

4, localized seizures: also known as simple seizures, manifested as a part of the body rhythmic tics, lasts for a few seconds, clear consciousness, if the epilepsy discharge expansion, can be extended to the body or body.

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