liposarcoma
Introduction
Introduction to liposarcoma Liposarcoma is a common type of malignant soft tissue sarcoma, which is more common in patients aged 30-70 years. More men than women, limbs, especially thighs, buttocks, upper limbs, retroperitoneum, head, neck, more than 3 ~ 10cm in diameter, the size of the large peritoneal can reach more than 20cm, the tumor is often nodular, or Leafy, soft or slightly hard. basic knowledge The proportion of illness: the prevalence rate is about 0.002% Susceptible people: the most affected by the age of 50 Mode of infection: non-infectious complication:
Cause
The cause of liposarcoma
Soft tissue tumors (30%):
It is derived from mesenchymal cells in which fat cells differentiate into adipocytes, so heterotrophic fat cells with different degrees of differentiation, all containing lipids can be divided into four types according to the degree and type of differentiation of tumor cells: well-differentiated mucus-like Round cell type and polymorphism, but tumors usually have a mixture of polymorphic cells.
Age difference (27%):
More common in patients aged 30 to 70 years, the most common incidence in the 50-year-old. More men than women. Limbs, especially thighs, buttocks, upper limbs, retroperitoneum, head, neck, more than 3 ~ 10cm in diameter, the diameter of the posterior peritoneum can reach more than 20cm, the tumor is often nodular, or lobulated, soft Or a little harder.
Lesion:
The presence of adipose tissue is likely to occur, with fat sarcoma occurring in the limbs accounting for 60%, the retroperitoneal space accounting for 15%, and the trunk subcutaneously 15%. The primary liposarcoma of the liver is extremely rare.
Prevention
Liposarcoma prevention
There are no effective preventive measures for this disease, mainly the diet should be light, eat less high-fat foods.
Complication
Liposarcoma complications Complication
Complications are complex and diverse, depending on the location of the tumor. The disease is a malignant tumor, and malignant metaplasia is the most serious complication.
Symptom
Symptoms of liposarcoma Common symptoms Painless hard solid nodules Single solid nodules Hepatic droop
More common in patients aged 30 to 70 years, the most common incidence in the 50-year-old. More men than women. Limbs, especially thighs, buttocks, upper limbs, retroperitoneum, head, neck, more than 3 ~ 10cm in diameter, the diameter of the posterior peritoneum can reach more than 20cm, the tumor is often nodular, or lobulated, soft Or a little harder.
Liposarcoma is the second common soft tissue sarcoma. Males are slightly more than females and can occur at any age, but most are over 40 years old. This disease rarely occurs in the abdominal cavity and thigh soft tissue, but it rarely occurs in it. There are also reports of trunk and limbs, and very few cases occur on the basis of the original lipoma.
It usually occurs in deep intermuscular soft tissue, which is characterized by a large mass and unclear margin. The liposarcoma can grow very hard and hard, unless the patient is late, the skin is rarely affected.
30% to 40% of patients with poor histological differentiation have metastasis, while those with good differentiation have less metastasis. Although they can also be transferred to the liver, bone marrow, and central nervous system, lungs are common metastatic sites.
Examine
Examination of liposarcoma
First, the laboratory examination: Liver primary liposarcoma liver function damage appeared late, enzymology and AFP, CEA and other tumor markers were negative, patients often found in the right upper quadrant pain, large liver after imaging examination can be Initial diagnosis, but a clear diagnosis requires liver biopsy.
Second, other auxiliary inspection methods:
1, B-ultrasound examination can see a large and uniform strong echo zone in the liver.
2, CT examination showed a small edge of the low-density area CT value is small, up to -90Hu, is the lowest CT value of intrahepatic tumors, no enhancement after injection of contrast agent.
3. MRI checks that the T1T2 weighted image is in the high signal region.
Diagnosis
Diagnosis and diagnosis of liposarcoma
Ultimately, relying on pathological diagnosis, the main identified tumors should be differentiated from common and mucinous types in malignant fibrous histiocytoma and polymorphisms in rhabdomyosarcoma.
