soil-fertilizer symmetrical acropigmentation
Introduction
Introduction to soil symmetry acral pigmentation Symmetrical acral dysplasia (Doubleacropigmentation of Dohi) is symmetrical in the hand, freckle-like pigmentation and hypopigmentation of the foot. basic knowledge The proportion of illness: 0.001% Susceptible people: no specific population Mode of infection: non-infectious Complications: depression
Cause
Symptoms of symmetry acral pigmentation in soil and fertilizer
Genetic (30%):
The disease belongs to a rare autosomal dominant genetic disease, which can be associated with a variety of hereditary types, and is related to various factors such as environmental factors and autoimmune factors.
pathology
The pathogenesis is still not clear. For a rare autosomal dominant inheritance. Histopathological examination: the basal layer of pigment particles increased, the hypopigmentation area was less, and the phagocytic cells in the dermis increased.
Prevention
Soil and fertilizer symmetry acral pigmentation prevention
The disease belongs to a rare autosomal dominant genetic disease, which can be associated with a variety of hereditary types, and is related to various factors such as environmental factors and autoimmune factors. Therefore, it is impossible to prevent the primary cause. Therefore, early detection, early diagnosis and early treatment are of great significance for the prognosis of this disease. At the same time, it should avoid or reduce the illumination, and to a certain extent, can reduce the onset of pigmentation. Pay attention to the nutrition in daily life, diversify the food as much as possible, and eat high-protein, multi-vitamin, low-animal fat, digestible food and fresh fruits and vegetables. Eat old-fashioned or irritating things, eat less smoked, roasted, marinated, fried, salty foods, staple foods and grains to ensure nutritional balance.
Complication
Symptoms of symmetry acral pigmentation in soil and fertilizer Complications depression
The disease belongs to skin pigmentation, generally does not have malignant manifestations, and does not induce or directly cause other diseases due to the disease, so there is no clinical complications. However, due to the change of skin morphology, some patients with low psychological quality may be damaged by the beauty of the skin, and in the absence of communication, it may cause depression. Although it is rare in clinical practice, it should be alert.
Symptom
Symmetrical symphysis of acral pigmentation symptoms common symptoms freckle pigmentation slow growth
From infants and young children, puberty is obvious, slow progress, lasting for many years, occurs at the extremities of the extremities, rashes are spotted to lentil-sized brown spots, do not fuse, seem freckles, darken after summer sun, light is limited to Hand, foot, back; heavy can be applied to the face, forearm, calf, chest back, abdomen and so on. Oral mucosa can also be rash, no symptoms, reticular leukoplakia and pigment spots in the back of the hands and feet, more men than women, the same family has the same patient, and some children can appear at the fold or the distal end of the finger after birth. Depigmentation of pigment.
Examine
Physico-symmetric symmetry of acral pigmentation
Histopathology: basal layer pigment particles increased, hypopigmented areas were less, and phagocytic cells in the dermis increased.
Diagnosis
Diagnosis and differentiation of symmetry acral pigmentation in soil and fertilizer
diagnosis
According to the clinical manifestations, the characteristics of skin lesions and histopathological features can be diagnosed.
Differential diagnosis
1. Secondary pigmentation abnormalities after frostbite are caused by repeated inflammation, leukoplakia is more prominent than dark spots, no freckles-like rash on the face, no genetic characteristics.
2. Coloring dry skin disease In addition to pigmentation changes, there are dry skin, atrophy, telangiectasia and skin flushing.
3. Reticulated acral pigmentation Freckle-like pigmentation spots on the dorsal side of the extremities are particularly obvious and dense in the lateral part of the iliac crest. The pigmented spots are slightly concave compared with normal skin, but consistent with the sulcus, no pigmentation spots, and distribution. More extensive.
