Non-01 Vibrio cholerae enteritis
Introduction
Introduction to non-01 Vibrio cholera enteritis Non-01 Vibrio cholera enteritis is an intestinal infectious disease caused by non-01 Vibrio cholerae, and the clinical manifestations are gastroenteritis type and dysentery type. In recent years, with the decline of the incidence of cholera, the scope, intensity and pathogenicity of the non-01 group of Vibrio cholerae infection have an increasing trend, which has gradually attracted people's attention. In recent years, it has been reported that cholera epidemics in South Asia are not cholera. The Vibrio 01 group and the non-01 group Vibrio cholerae were agglutinated by the diagnostic serum. This epidemic strain is still a new serotype of Vibrio cholerae, which has not been recorded yet, so it is named 0139 Vibrio cholerae. basic knowledge The proportion of sickness: 0.00001% Susceptible people: no special people Mode of infection: contagious Complications: pulmonary edema, acute renal failure
Cause
Non-01 Vibrio cholerae enteritis cause
(1) Causes of the disease
The biological characteristics of non-01 Vibrio cholerae are similar to those of Vibrio cholerae. Their flagellar antigens are also the same, but the bacterial antigens are different. According to the difference of O antigens, the serogroups can be divided into 02~0138, and 0139 is different from the former serogroup. The strain has strong resistance in vitro.
(two) pathogenesis
Some people think that this strain can produce a Shiga toxin-like cytotoxin, which may be an important virulence factor, and it has been confirmed that some strains can produce cholera enterotoxin or heat-resistant enterotoxin.
Prevention
Non-01 Vibrio cholerae enteritis prevention
Strictly isolate patients, conduct strict inspections on employees in the service industry such as diet, timely discover and treat carriers, prevent fecal contamination of water sources, disinfect drinking water that may be polluted, and cook boiled seafood or foods that may be contaminated. Thoroughly, strictly separate raw and cooked, and put "good disease into the mouth".
Complication
Non-01 cholera vibri enteritis complications Complications pulmonary edema acute renal failure
First, acute pulmonary edema: its clinical manifestations are sudden severe breathing difficulties, sitting breathing, with cough, often coughing out pink foam-like sputum; patients irritability, cyanosis, sweating, heart rate, lungs It is covered with wet rales and wheezing. In severe cases, it can cause syncope and cardiac arrest. Metabolic acidosis can lead to high pulmonary circulation, which is aggravated by the addition of a large amount of alkali-free saline.
Second, renal failure: According to the rapid onset of the attack is divided into acute and chronic two, acute renal failure is the two kidneys lost excretory function in a short time. Because shock is not corrected in time and hypokalemia, it is characterized by decreased urine output and azotemia. In severe cases, urinary closure occurs, which can be caused by uremia.
Symptom
Non-01 Vibrio cholerae enteritis symptoms common symptoms dehydration nausea diarrhea abdominal pain blood pressure drop watery stool
1. Gastroenteritis type: diarrhea, nausea, vomiting and watery stools, etc., vomiting and diarrhea may be accompanied by dehydration and blood pressure drop.
2. Dysentery type: manifested as fever, abdominal pain and mucus, tenderness in the left lower abdomen, and a large number of white blood cells in the stool.
Examine
Non-01 cholera vibrio enteritis examination
A large number of white blood cells can be seen in the stool examination, and there are proteins or cells and casts in urine.
Blood urea nitrogen is elevated, H6, red blood cells, white blood cells are elevated, and blood potassium and chloride can be normal or decreased.
Diagnosis
Diagnosis and identification of non-01 Vibrio cholera enteritis
1. Clinical features: diarrhea, vomiting, watery stool or accompanied by fever, abdominal pain, mucus.
2. Epidemiology: There is a history of eating contaminated food or seafood.
3. Experimental diagnosis: Bacterial culture can be carried out by using alkaline peptone, alkali plate, blood plate, etc., and must be identified by serology, gas chromatography and biochemical reaction with Vibrio cholerae 01.
It is mainly related to cholera, acute bacillary dysentery, Salmonella infection, Vibrio parahaemolyticus enteritis, etc., all relying on pathogenic examination.
