Bone Schwannoma
Introduction
Introduction to skeletal sheath tumor Osteosporosis is a benign tumor produced by intraosseous nerve sheath cells, which is rare. Occurs in the mandible, atlas, ulnar and humeral shaft, mostly young and middle-aged men aged 20 to 50 years, with slow tumor development and long course of disease. basic knowledge Sickness ratio: 0.0001% Susceptible people: young and middle-aged men who are 20 to 50 years old Mode of infection: non-infectious Complications: fracture
Cause
Cause of skeletal sheath tumor
(1) Causes of the disease
A benign tumor produced by intrathecal nerve sheath cells.
(two) pathogenesis
The tumor originates from the nerve sheath. In the early stage, the relationship between the tumor and the nerve can be seen. The schwannomas in the lumbosacral spine can occur under the epidural or subarachnoid. The tumor is large and difficult to operate. To understand the relationship with the nerve, the tumor tissue color is reddish or grayish yellow, soft and brittle, mucinous, and the large volume of the tumor often has extensive degeneration, forming a cavity, which can be expressed under the microscope as two types of tissue: 1 Tumor cells are bundled in parallel with each other in a fence shape, the cell nucleus is fine and long, and the cells are rich in elongated reticular fibers. 2 The tumor cells are arranged disorderly and loose, and the cells and fibers contain liquid, and the liquid can aggregate to form a cyst. The schwannomas located in the bone are prone to extensive degeneration. This type is more common. In addition, old bleeding and foam cells can be seen, sometimes large and deeply stained nuclei, non-malignant manifestations.
Prevention
Osteosphingoma prevention
Preventing the occurrence of tumors is the key to preventing this disease. Tumor prevention refers to reducing the mortality of tumors by reducing the incidence of tumors. Specifically, it aims to prevent tumor infection-related infectious factors, change unhealthy lifestyles, exercise properly, maintain a happy spirit, and use certain medical interventions to reduce tumors by targeting a variety of environmental cancer risk factors. Risk of onset.
Complication
Osteosphingoma complications Complications
Often and can be associated with rational fractures.
Symptom
Symptoms of skeletal schwannomas Common symptoms Neuropathic pain, numbness, osteoporosis, low back pain, sciatica
Most of the patients are middle-aged men. The main symptoms are neuropathic pain and numbness. The symptoms are mild and the course of disease is long. The local bones are swollen. If the bones are broken, local tumors can be produced and pathological fractures can occur. Nerve dry running nodules, pressure caused by nerve pain and numbness, generally no spontaneous pain or discomfort, lumbosacral schwannomas, can produce low back pain or sciatica, often misdiagnosed; can also cause bladder, rectum Dysfunction and other symptoms.
Examine
Examination of skeletal schwannomas
X-ray findings are uniform osteolytic bone destruction, and the boundary is clear and a thin layer of hardened bone is visible. The tumor causes the bone to swell and even break through the bone to form a soft tissue tumor. The large tumor can be multi-atrial. However, there is no calcification or ossification in the lesion area. If it originates from the periosteum, it will form an impression from the extra-bone to the bone, and even wear the bone. CT shows that the schwannomas are a mass with uneven density, and its density is close to that of water. The density to the muscle density is not equal, the boundary is neat, and the irregular enhancement after angiography is also a signal unevenness on the MRI image. The T1 weighted signal is high or low. If the cyst is cystic or necrotic, the T2 weighting can be expressed as Obvious signal, schwannomas can only be diagnosed by imaging findings, intraspinal schwannomas can be diagnosed by spinal angiography, and the nerve pores are enlarged.
Diagnosis
Diagnosis and diagnosis of skeletal schwannomas
According to medical history, clinical manifestations and X-ray findings, the possibility of this disease should be thought of. The spinal canal canopy can be diagnosed by spinal canal angiography, CT and MRI are helpful for diagnosis, and finally rely on pathological diagnosis.
